Squalene Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Squalene Market Report is Segmented by Source (Animal Source, Vegetable Source, Biosynthetic, and Other Sources), End-User Industry (Cosmetics, Food, Pharmaceutical, and Other End-User Industries), and Geography (Asia-Pacific, North America, Europe, South America, and Middle East and Africa). The Report Offers Market Size and Forecasts in Value (USD) for all the Above Segments.

Squalene Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Squalene Market Size

Squalene Market Summary
Study Period 2019 - 2030
Market Size (2025) USD 173.20 Million
Market Size (2030) USD 231.35 Million
CAGR (2025 - 2030) 5.96 %
Fastest Growing Market Asia Pacific
Largest Market Europe
Market Concentration High

Major Players

Squalene Market Major  Players

*Disclaimer: Major Players sorted in no particular order

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Squalene Market Analysis

The Squalene Market size is estimated at USD 173.20 million in 2025, and is expected to reach USD 231.35 million by 2030, at a CAGR of 5.96% during the forecast period (2025-2030).

The squalene industry is experiencing a significant transformation driven by increasing environmental consciousness and sustainability initiatives. Major manufacturers are actively transitioning from traditional shark-liver-based squalene to plant-based and biotechnology-derived alternatives. This shift is exemplified by strategic collaborations like the May 2023 partnership between Croda International Plc and Amyris for the development and distribution of biotechnology-derived pharmaceutical-grade squalene. The industry's commitment to sustainability is further demonstrated by innovations such as Evonik Industries' December 2022 launch of PhytoSquene, a non-animal-derived squalene suitable for vaccines and pharmaceutical applications.


The market landscape is being reshaped by technological advancements in extraction and production methods, particularly in the development of plant-based alternatives. Companies are investing heavily in research and development to improve extraction efficiency from olive oil, amaranth oil, and sugarcane-based sources. The global pharmaceutical market, valued at USD 1.21 trillion in 2022, has created substantial opportunities for squalene manufacturers, especially in vaccine adjuvant applications. This has led to increased focus on developing pharmaceutical-grade squalene that meets stringent quality and regulatory requirements.


Consumer preferences are increasingly shifting towards natural and sustainable ingredients across industries, particularly in personal care and cosmetics. The European cosmetics market, worth EUR 88 billion in 2022, demonstrates the significant potential for natural ingredients like squalene in beauty and personal care applications. This trend is particularly evident in major markets like China, where L'Oréal's brands have maintained leading positions across beauty categories on Tmall, highlighting the growing demand for premium, naturally-derived ingredients such as squalene as a cosmetic emollient.


The nutraceutical sector is emerging as a promising growth avenue for squalene, driven by increasing health consciousness and demand for natural supplements. This trend is particularly pronounced in regions like the UAE, where studies by the Dubai Health Authority indicate that vitamin D deficiency affects approximately 90% of the population, creating opportunities for supplement manufacturers to incorporate squalene as a nutraceutical ingredient into their formulations. The industry is witnessing a surge in research and development activities focused on enhancing the bioavailability and efficacy of squalene in nutritional applications, leading to innovative product formulations and delivery systems.

Segment Analysis: Source

Vegetable Source Segment in Squalene Market

The vegetable source segment dominates the global squalene market, holding approximately 37% of the market share in 2024. This segment's leadership position is primarily driven by increasing consumer preference for plant-based products and growing environmental concerns regarding shark-based squalene. Olive oil serves as the primary source for vegetable-based squalane, followed by amaranth oil and palm oil. The segment is also experiencing the fastest growth trajectory in the market, projected to grow at around 7% during 2024-2029, driven by expanding applications in cosmetics and personal care products. Major cosmetic manufacturers are increasingly shifting towards vegetable-based squalane due to its superior stability, non-greasy consistency, and lighter texture compared to animal-derived alternatives. The segment's growth is further supported by technological advancements in extraction methods and increasing investments in sustainable sourcing practices.

Market Analysis of Squalene Market: Chart for Source

Animal Source Segment in Squalene Market

The animal source segment maintains a significant presence in the global squalene market, primarily derived from shark liver oil. This segment continues to serve traditional markets and specific applications where animal-derived squalene is preferred. However, the segment faces increasing scrutiny due to environmental concerns and sustainability issues, leading to a gradual shift towards alternative sources. Despite these challenges, the segment maintains its position in certain pharmaceutical applications, particularly in vaccine adjuvants, where specific properties of shark-derived squalene are valued. The segment's market dynamics are influenced by strict fishing regulations, conservation efforts, and growing pressure from environmental organizations to reduce shark fishing practices.

Remaining Segments in Source Segmentation

The biosynthetic segment represents an emerging alternative in the squalene market, offering a sustainable solution that addresses both environmental concerns and supply chain challenges. This segment utilizes advanced biotechnology processes, including fermentation of sugarcane and other biomass sources, to produce squalane. Companies are increasingly investing in research and development to improve production efficiency and reduce costs associated with biosynthetic squalane production. The segment is particularly gaining traction in pharmaceutical applications, especially in vaccine development, where consistent quality and reliable supply chains are crucial. The advancement of synthetic biology and fermentation technologies continues to enhance the segment's potential as a viable alternative to traditional sources.

Segment Analysis: End-User Industry

Cosmetics Segment in Squalene Market

The cosmetics segment dominates the global squalene market, accounting for approximately 70% of the total market share in 2024. This segment's commanding position is driven by the extensive use of squalane as a cosmetic emollient in various skincare and personal care applications, including moisturizers, anti-aging creams, sunscreens, and hair care products. The segment's growth is further propelled by increasing consumer preference for natural and organic beauty products, with squalane being valued for its moisturizing and skin-protective properties. Major cosmetic companies worldwide are incorporating squalane into their formulations, particularly in premium skincare products. The segment is also experiencing the fastest growth rate in the market, projected to expand at around 7% from 2024 to 2029, driven by rising consumer awareness about skincare, growing disposable incomes, and the expanding beauty and personal care industry across both developed and emerging markets.

Remaining Segments in End-User Industry

The food and pharmaceutical segments represent significant applications in the squalene market, each serving distinct purposes. The food segment utilizes squalene primarily as a lipid supplement, leveraging its potential health benefits, including cholesterol management and immune system support. This segment has gained traction due to increasing consumer focus on preventive healthcare and wellness supplements. The pharmaceutical segment, while smaller in market share, plays a crucial role in vaccine development and drug delivery systems, with squalene being used as an important adjuvant in vaccine formulations. Both segments benefit from ongoing research and development activities exploring new applications of squalene in functional foods and pharmaceutical formulations, contributing to the overall market growth.

Squalene Market Geography Segment Analysis

Squalene Market in Asia-Pacific

The Asia-Pacific region represents a significant market for squalene, driven by the robust growth of the cosmetics and personal care industries across major economies. China leads the regional market with its expanding pharmaceutical and cosmetics sectors, followed by significant contributions from Japan, India, and South Korea. The region's growth is supported by increasing consumer awareness about natural ingredients in personal care products and the rising demand for premium skincare solutions. The presence of major cosmetic manufacturers and growing research activities in pharmaceutical applications further strengthen the market dynamics in this region.

Market Analysis of Squalene Market: Forecasted Growth Rate by Region

Squalene Market in China

China dominates the Asia-Pacific squalene market, holding approximately 39% of the regional market share. The country's beauty market has shown remarkable resilience and growth, particularly in the skincare segment. The increasing adoption of natural and organic beauty products, coupled with rising disposable incomes and changing consumer preferences, drives market growth. China's pharmaceutical sector, being one of the largest globally, further contributes to market expansion through increased demand for vaccine adjuvants and drug delivery systems. The country's strong manufacturing capabilities and growing research and development investments in biotechnology continue to strengthen its position in the regional market.

Squalene Market Growth Potential in India

India emerges as the fastest-growing market in the Asia-Pacific region, with an expected growth rate of approximately 7% during 2024-2029. The country's rapidly expanding cosmetics and personal care industry, coupled with increasing health consciousness among consumers, drives market growth. India's pharmaceutical sector, being one of the largest globally in terms of volume, presents significant opportunities for squalene applications in vaccine development and drug delivery systems. The government's support for domestic manufacturing and increasing investments in biotechnology research further enhance market prospects in the country.

Squalene Market in North America

The North American squalene market demonstrates strong growth potential, supported by advanced pharmaceutical research, a robust cosmetics industry, and increasing consumer preference for natural ingredients. The United States leads the regional market, followed by Canada and Mexico. The region's market is characterized by significant investments in research and development, particularly in biotechnology and pharmaceutical applications. The presence of major cosmetic manufacturers and growing awareness about sustainable sourcing practices further shapes market dynamics in this region.

Squalene Market in United States

The United States maintains its position as the largest squalene market in North America, commanding approximately 73% of the regional market share. The country's pharmaceutical industry, being one of the largest globally, drives significant demand for squalene in vaccine adjuvants and drug delivery systems. The robust presence of major cosmetic manufacturers, coupled with increasing consumer preference for natural and sustainable beauty products, further strengthens market growth. The country's advanced research infrastructure and continuous innovations in biotechnology applications contribute to its market leadership.

Squalene Market Growth Potential in United States

The United States also leads in terms of growth potential in North America, with an anticipated growth rate of approximately 6% during 2024-2029. The country's strong focus on research and development in pharmaceutical applications, particularly in vaccine development, drives market expansion. The growing trend toward natural and sustainable ingredients in cosmetics and personal care products further accelerates market growth. The presence of well-established distribution networks and increasing investments in biotechnology contribute to the market's dynamic growth trajectory.

Squalene Market in Europe

Europe represents a crucial market for squalene, characterized by a strong presence in both pharmaceutical and cosmetics applications. The region benefits from advanced research capabilities and a strong regulatory framework supporting sustainable sourcing practices. Germany, France, the United Kingdom, and Italy emerge as key markets, each contributing significantly to regional growth. The region's focus on sustainable and natural ingredients in cosmetics, coupled with advanced pharmaceutical research, drives market development.

Squalene Market in Germany

Germany maintains its position as the largest squalene market in Europe, driven by its robust pharmaceutical and cosmetics industries. The country's strong focus on research and development, particularly in sustainable sourcing methods, strengthens its market leadership. Germany's well-developed distribution networks and the presence of major cosmetic manufacturers contribute to market growth. The increasing consumer preference for natural and sustainable beauty products further enhances market development.

Squalene Market Growth Potential in Germany

Germany also leads Europe in terms of growth potential, supported by continuous innovations in biotechnology and sustainable sourcing methods. The country's strong emphasis on research and development in pharmaceutical applications drives market expansion. The growing trend toward natural and organic cosmetics, coupled with increasing investments in sustainable production methods, contributes to market growth. Germany's advanced manufacturing capabilities and strong regulatory framework support sustained market development.

Squalene Market in South America

The South American squalene market shows promising growth potential, driven by expanding cosmetics and pharmaceutical industries across the region. Brazil emerges as both the largest and fastest-growing market in the region, followed by Argentina. The region's rich biodiversity and increasing focus on natural ingredients in cosmetics support market growth. The growing pharmaceutical sector, particularly in vaccine development, further contributes to market expansion. Increasing consumer awareness about natural and sustainable products, coupled with rising disposable incomes, shapes market dynamics in South America.

Squalene Market in Middle East and Africa

The Middle East and Africa region presents emerging opportunities in the squalene market, driven by a growing cosmetics industry and increasing healthcare investments. Saudi Arabia represents the largest market in the region, while South Africa shows the fastest growth potential. The region's market is characterized by increasing awareness about natural ingredients in personal care products and growing pharmaceutical research activities. The presence of strong distribution networks and rising investments in healthcare infrastructure support market development. The region's growing focus on sustainable sourcing practices and increasing demand for premium cosmetic products further contribute to market expansion.

Squalene Industry Overview

Top Companies in Squalene Market

The global squalane market is characterized by continuous product innovation and strategic developments among key players like Amyris, Sophim, and Kishimoto Special Liver Oil. Companies are increasingly focusing on developing sustainable production methods, particularly moving away from shark-derived squalene towards plant-based and biotechnology-derived alternatives. Operational excellence is being achieved through integrated manufacturing capabilities and robust logistics networks serving international markets. Strategic partnerships and collaborations, especially in the pharmaceutical and cosmetic sectors, are becoming increasingly common to strengthen market positions. Companies are expanding their geographical presence through new manufacturing facilities and distribution networks, while also investing in research and development to enhance product quality and application scope. The emphasis on upcycling and circular economy practices is gaining prominence, with companies developing innovative processes to extract squalane from waste materials.

Consolidated Market with Strong Regional Players

The squalene market exhibits a consolidated structure with a mix of global conglomerates and specialized manufacturers. Major players have established strong positions through dedicated manufacturing processes, strategic marketing approaches, and robust customer relationships across various end-user industries. The market is characterized by the presence of both large-scale international players with integrated operations and smaller regional specialists focusing on specific application segments. Companies with established research and development capabilities and proprietary technologies hold significant advantages in terms of product quality and market penetration.


The industry has witnessed strategic mergers and acquisitions aimed at strengthening market positions and expanding product portfolios. Companies are increasingly focusing on vertical integration to gain better control over raw material supplies and distribution channels. The competitive landscape is further shaped by regional players who leverage their local market knowledge and established distribution networks. Market leaders are maintaining their positions through continuous innovation in production processes, while also focusing on sustainability certifications and quality standards to meet evolving customer demands.

Innovation and Sustainability Drive Future Success

Success in the squalene market increasingly depends on developing sustainable sourcing methods and efficient production processes. Companies need to focus on establishing strong research and development capabilities to create innovative extraction methods and improve product quality. Building strong relationships with end-users in the cosmetics, pharmaceuticals, and food industries is becoming crucial for maintaining market share. Regulatory compliance, particularly regarding environmental protection and sustainable sourcing, is emerging as a key differentiator for market players. Investment in advanced manufacturing technologies and quality control systems is essential for maintaining competitive advantages.


For new entrants and smaller players, success lies in identifying and serving niche market segments with specialized products. Developing alternative raw material sources and eco-friendly production methods can provide significant competitive advantages. Companies need to focus on building strong distribution networks and establishing partnerships with key industry players to gain market access. Understanding and adapting to regional market dynamics and customer preferences is crucial for success. The ability to offer customized solutions and maintain high-quality standards while ensuring competitive pricing will be critical for gaining market share in this evolving industry. The inclusion of squalane as a skincare ingredient and nutraceutical ingredient is becoming increasingly significant, offering new opportunities for product diversification and market expansion.

Squalene Market Leaders

  1. Amyris, Inc.

  2. Kishimoto Special Liver Oil Co. Ltd.

  3. Sophim

  4. Nucelis

  5. Oleicfat S.L.

  6. *Disclaimer: Major Players sorted in no particular order
Global Squalene Market  Concentration
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Squalene Market News

  • October 2023: Evonik Industries AG introduced PhytoSquene, a GMP-quality, plant-based squalene. With this launch, Evonik aims to meet the growing demand for a reliable commercial supply of squalene, a substance traditionally extracted from shark liver oil, for pharmaceutical uses.
  • May 2023: Amyris announced its partnership with Croda International PLC (Croda) to supply biotechnology-derived, pharmaceutical-grade squalene used in adjuvants to boost immune responses.
  • June 2022: Amyris announced the inauguration of the production of 13 molecules, including squalene, at its plant in Brazil. The company also stated that it developed a process to produce sugarcane-derived squalene as an alternative to non-sustainable shark-derived squalene.

Squalene Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Drivers
    • 4.1.1 Growing Demand from Cosmetics Sector
    • 4.1.2 Rising Demand from the Pharmaceutical Industry
    • 4.1.3 Other Drivers
  • 4.2 Market Restraints
    • 4.2.1 Shark Killing Concerns and Limitations
    • 4.2.2 Other Restraints
  • 4.3 Industry Value Chain Analysis
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Bargaining Power of Suppliers
    • 4.4.2 Bargaining Power of Buyers
    • 4.4.3 Threat of New Entrants
    • 4.4.4 Threat of Substitute Products and Services
    • 4.4.5 Degree of Competition

5. MARKET SEGMENTATION (Market Size in Value)

  • 5.1 By Source
    • 5.1.1 Animal Source
    • 5.1.2 Vegetable Source
    • 5.1.3 Biosynthetic
    • 5.1.4 Other Sources
  • 5.2 By End-user Industry
    • 5.2.1 Cosmetics
    • 5.2.2 Food
    • 5.2.3 Pharmaceuticals
    • 5.2.4 Other End-user Industries
  • 5.3 By Geography
    • 5.3.1 Asia-Pacific
    • 5.3.1.1 China
    • 5.3.1.2 India
    • 5.3.1.3 Japan
    • 5.3.1.4 South Korea
    • 5.3.1.5 Malaysia
    • 5.3.1.6 Thailand
    • 5.3.1.7 Indonesia
    • 5.3.1.8 Vietnam
    • 5.3.1.9 Rest of Asia-Pacific
    • 5.3.2 North America
    • 5.3.2.1 United States
    • 5.3.2.2 Canada
    • 5.3.2.3 Mexico
    • 5.3.3 Europe
    • 5.3.3.1 Germany
    • 5.3.3.2 United Kingdom
    • 5.3.3.3 France
    • 5.3.3.4 Italy
    • 5.3.3.5 Spain
    • 5.3.3.6 NORDIC Countries
    • 5.3.3.7 Turkey
    • 5.3.3.8 Russia
    • 5.3.3.9 Rest of Europe
    • 5.3.4 South America
    • 5.3.4.1 Brazil
    • 5.3.4.2 Argentina
    • 5.3.4.3 Colombia
    • 5.3.4.4 Rest of South America
    • 5.3.5 Middle East and Africa
    • 5.3.5.1 Saudi Arabia
    • 5.3.5.2 Qatar
    • 5.3.5.3 United Arab Emirates
    • 5.3.5.4 Nigeria
    • 5.3.5.5 Egypt
    • 5.3.5.6 South Africa
    • 5.3.5.7 Rest of Middle East and Africa

6. COMPETITIVE LANDSCAPE

  • 6.1 Mergers and Acquisitions, Joint Ventures, Collaborations, and Agreements
  • 6.2 Market Share (%)**/ Ranking Analysis
  • 6.3 Strategies Adopted by Leading Players
  • 6.4 Company Profiles
    • 6.4.1 Aasha Biochem
    • 6.4.2 Amyris Inc.
    • 6.4.3 Arbee
    • 6.4.4 Efpbiotek
    • 6.4.5 Evonik Industries AG
    • 6.4.6 Gihi Chemicals Co. Limited
    • 6.4.7 Gracefruit Limited
    • 6.4.8 Kishimoto Special Liver Oil Co. Ltd
    • 6.4.9 Kuraray Co. Ltd
    • 6.4.10 Nucelis
    • 6.4.11 Oleicfat SL
    • 6.4.12 Sophim
    • 6.4.13 Unilong Industry Co. Ltd
    • 6.4.14 Vestan SA
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

  • 7.1 Research and Development on Squalene for Oncology Uses
  • 7.2 Other Opportunities
**Subject to Availability
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Squalene Industry Segmentation

Squalene, a colorless and odorless organic compound, is commercially extracted from shark liver oil and is non-toxic. Due to its non-toxic nature, squalene has extensive applications in personal care. In the cosmetics industry, squalene oil combats free radicals, which are known to damage the skin and accelerate aging. Furthermore, squalene serves as an ingredient in adjuvants for various vaccines, such as those for influenza and COVID-19, boosting their efficacy.

The squalene market is segmented by source, end-user industry, and geography. By source, the market is segmented into animal source, vegetable source, biosynthetic, and other sources. By end-user industry, the market is segmented into cosmetics, food, pharmaceuticals, and other end-user industries. The report also covers the market size and forecasts for the squalene market in 27 countries across major regions. For each segment, the market size and forecasts are provided on the basis of value (USD).

By Source Animal Source
Vegetable Source
Biosynthetic
Other Sources
By End-user Industry Cosmetics
Food
Pharmaceuticals
Other End-user Industries
By Geography Asia-Pacific China
India
Japan
South Korea
Malaysia
Thailand
Indonesia
Vietnam
Rest of Asia-Pacific
North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
NORDIC Countries
Turkey
Russia
Rest of Europe
South America Brazil
Argentina
Colombia
Rest of South America
Middle East and Africa Saudi Arabia
Qatar
United Arab Emirates
Nigeria
Egypt
South Africa
Rest of Middle East and Africa
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Squalene Market Research FAQs

How big is the Squalene Market?

The Squalene Market size is expected to reach USD 173.20 million in 2025 and grow at a CAGR of 5.96% to reach USD 231.35 million by 2030.

What is the current Squalene Market size?

In 2025, the Squalene Market size is expected to reach USD 173.20 million.

Who are the key players in Squalene Market?

Amyris, Inc., Kishimoto Special Liver Oil Co. Ltd., Sophim, Nucelis and Oleicfat S.L. are the major companies operating in the Squalene Market.

Which is the fastest growing region in Squalene Market?

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Squalene Market?

In 2025, the Europe accounts for the largest market share in Squalene Market.

What years does this Squalene Market cover, and what was the market size in 2024?

In 2024, the Squalene Market size was estimated at USD 162.88 million. The report covers the Squalene Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Squalene Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Squalene Market Research

Mordor Intelligence offers comprehensive expertise in analyzing the rapidly evolving squalane market. We deliver detailed insights through an easy-to-read report PDF available for download. Our research thoroughly examines the applications of squalane as a premium skincare ingredient and cosmetic emollient. Additionally, we explore its emerging role as a lipid supplement in various industries.

The report provides stakeholders with actionable intelligence on market dynamics. It includes a detailed analysis of squalane applications in both cosmetic and nutraceutical ingredient sectors. Our extensive coverage of the nutraceutical ingredient market offers valuable insights for manufacturers, suppliers, and investors. This is supported by robust data analysis and future market projections. The comprehensive assessment helps businesses identify growth opportunities and optimize their market strategies through detailed industry analysis and trend forecasting.