Market Trends of Sickle Cell Treatment Industry
Blood Transfusion Segment is Expected to Witness Significant Growth Over the Forecast Period
The blood transfusion segment is expected to witness healthy growth over the forecast period. The growth of this segment is attributed to the high demand for blood transfusion in sickle cell treatment and the increase in the prevalence of SCD. Blood transfusions enable the supply of normal red blood cells, which can enhance hemoglobin levels to improve oxygen delivery in the body, thereby reducing sickle cell blockage in blood vessels and minimizing the desire to make more sickle cells.
The rising prevalence of sickle cell disease is the major factor driving the segment's growth. According to an article published by HemaSphere in August 2022, a study in India showed a very high prevalence of sickle cell disease among the non-tribal people in Chattisgarh, India. Thus, the rising prevalence of sickle cell disease is expected to drive the segment during the forecast period.
The increasing usage of blood transfusion to manage the disease is also expected to impact the segment positively. For instance, according to the data updated by CDC in September 2021, if a person has sickle cell disease (SCD), then one or more blood transfusions (healthy blood from a donor put into your body) are required during the lifetime. During a blood transfusion, the patient's blood and the donated blood must have matching antigens or special proteins on the surface of each red blood cell.
The rising R&D for sickle cell disease is also expected to boost the segment's growth. For instance, according to the data updated by clinicaltrials.gov in February 2023, currently, there are 58 ongoing and active clinical trials for blood transfusion in sickle cell disease. Thus, the large number of clinical trials is expected to boost the adoption of blood transfusion for this treatment.
Thus, factors such as the rising prevalence of sickle cell disease, the increasing usage of blood transfusion for the management of the disease, and the rising R&D for sickle cell disease are expected to enhance the segment's growth.
North America is Expected to Hold a Significant Share in the Sickle Cell Treatment Market During the Forecast Period
North America is expected to hold a significant share of the overall sickle cell treatment market, with the United States being the major contributor. The growth in the region is attributed to improving access to SCD treatment and potential pipeline candidates. The strong government support in the United States will further foster the market's development. The rising prevalence of sickle cell disease in the region, the increasing number of clinical trials, and the rising product launches are expected to boost the market's growth in the region.
According to the data updated by CDC in May 2022, sickle cell disease (SCD) affects approximately 100,000 Americans every year, and SCD occurs among about 1 out of every 365 black or African American births. The source also stated that SCD occurs among about 1 out of every 16,300 Hispanic American births, and about 1 in 13 black or African-American babies is born with sickle cell trait (SCT). Similarly, according to an article published by the Canadian Pediatric Society in February 2022, sickle cell disease (SCD) is considered one of the most common human genetic diseases, and it affects at least 5,000 individuals in Canada every year.
The increasing initiatives by the government are also expected to boost the market's growth in the region. For instance, in September 2022, the National Institutes of Health (NIH) granted a five-year, USD 7.7 million grant to support a new research project that seeks to lower barriers to healthcare for people with sickle cell disease (SCD).
The increasing developments by key market players are also expected to boost the market's growth. For instance, in May 2022, the US FDA awarded fast-track designation to Graphite Bio's GPH101. This investigational gene-editing therapy aims to correct the genetic mutation that causes sickle cell disease (SCD) and potentially cure the condition. In January 2022, Agios Pharmaceuticals launched a phase 2/3 trial called RISE UP to test its investigational therapy mitapivat (AG-348) in people with sickle cell disease (SCD).
Thus, factors such as the rising prevalence of sickle cell disease and the rising R&D are expected to boost the market's growth in the region.
