Post Operative Pain Management Market Size (2024 - 2029)

Post Operative Pain Management Market Analysis

The Post Operative Pain Management Market size is estimated at USD 40.46 billion in 2024, and is expected to reach USD 53.61 billion by 2029, growing at a CAGR of 5.79% during the forecast period (2024-2029).

Factors fueling the market's growth are the growing number of surgical procedures, the rising number of emergency hospital visits, the increasing demand for non-opioid-based analgesics, and the increasing focus on palliative care.

The growing number of surgical procedures drives the demand for post-operative pain management medications. For instance, according to the Canadian Institutes of Health Information data published in September 2023, in 2021-2022, Canada witnessed over 117,000 hip and knee replacements, marking a 5.9% increase from the preceding year. However, this figure remained below the pre-COVID-19 annual average. With such a huge increase in the number of surgeries performed across several countries, the market for post-operative pain management drugs is expected to exhibit substantial growth, as these medications play a crucial role in managing the pain caused by surgical procedures.

A study published in PubMed Central in January 2022 stated that, according to research conducted by the US Institute of Medicine in June 2022, post-operative pain was a common but often undertreated disease, with 80% of surgery patients experiencing post-operative pain and less than half of these patients reporting appropriate pain control. Furthermore, the study stated that, according to a nationwide survey, 39% of post-operative patients felt severe to terrible pain. Such unmet needs greatly highlight the need for post-operative pain management drugs to optimize palliative care among the patient population, thereby providing lucrative opportunities to prominent players within the market.

Additionally, strategic initiatives by the market players, such as product launches and research and development activities in the field of pain management, are expected to boost the market's growth. For instance, in April 2022, Assiut University started a trial to evaluate the population pharmacokinetics and pharmacodynamics of rectal dexmedetomidine niosomes for post-operative analgesia in pediatric cancer patients undergoing bone marrow biopsy and aspiration compared to the intravenous and rectal plain formulation.

In April 2022, Acadia Pharmaceuticals Inc. announced top-line results from a Phase 2 randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of ACP-044 for acute pain following bunionectomy surgery. The primary endpoint, a comparison of cumulative pain intensity scored over 24 hours between the ACP-044 1600 mg once daily, the ACP-044 400 mg four times daily, and the placebo treatment arms, was not met.

Thus, factors such as the rising number of surgical procedures and strategic initiatives by market players are expected to boost market growth over the forecast period. However, concerns about the overuse of opioids are a major factor restraining the market's growth.

Post Operative Pain Management Industry Segmentation

As per the report's scope, post-operative pain is defined as a complex response to tissue trauma post-surgical procedures. It comprises both surgery-related pain and pain linked with central nervous system hypersensitivity. The purpose of post-operative pain management medications is to minimize adverse effects while reducing or eliminating pain and discomfort.

The post-operative pain management market is segmented by drug class, route of administration, distribution channel, and geography. By drug class, the market is segmented into opioids, non-steroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase-2-selective inhibitors (COX-2) inhibitors, and other drug classes. By route of administration, the market is segmented into injectable, oral, topical, and other routes. By distribution channel, the market is segmented into hospital pharmacies, retail pharmacies, and other distribution channels. By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The report offers the value (USD) for all the above segments. The report also covers the estimated market sizes and trends for 17 countries across major regions globally.