Plasma Protein Therapeutics Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 30.49 Billion |
| Market Size (2029) | USD 39.85 Billion |
| CAGR (2024 - 2029) | 5.50 % |
| Fastest Growing Market | Asia-Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
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Plasma Protein Therapeutics Market Analysis
The Plasma Protein Therapeutics Market size is estimated at USD 30.49 billion in 2024, and is expected to reach USD 39.85 billion by 2029, growing at a CAGR of 5.5% during the forecast period (2024-2029).
The COVID-19 pandemic significantly impacted the plasma protein therapeutics market during the initial phase because of factors such as reduced plasma donations, shutdowns of laboratories and testing centers, and restrictions on medicine import and export. However, the sector has been recovering well since restrictions were lifted. The market is expected to grow due to increased plasma protein therapeutics product launches and associated research studies.
The major factors leading to the market's growth include the increasing prevalence of autoimmune disorders, immune deficiency disorders, neurological and bleeding disorders, and the rise in research and development in plasma protein. For instance, as per the 2022 update from NHF, approximately 400 male babies are born with hemophilia A every year. Furthermore, the growing investments in research & development programs by biotechnology and pharmaceutical companies are boosting the market growth. For instance, in November 2021, Biognosys launched the Next-Generation blood biomarker discovery solution. The improved service offers unprecedented depth, precision, and throughput, quantifying up to 3,000 proteins in plasma or serum.
Moreover, beneficial government initiatives, escalating awareness levels among blood donors, advanced protein fractioning procedures, greater per capita income in developed countries, and increased research partnerships are some of the drivers expected to increase market growth in the region. For instance, in October 2022, the Department of Health and Human Services (HHS) launched an innovation challenge to identify effective, evidence-based strategies to increase blood and plasma donations through sustainable, community-driven approaches. The challenge is part of HHS's 'Giving=Living campaign,' which aims to raise awareness of the importance of donating blood and to encourage Americans to develop new, regular donation habits. In October 2022, The ISBT Working Party on Global Blood Safety initiated the ICSPP as a global coalition to advance access to safe plasma proteins in Low- and middle-income countries. The alliance is likely to support national initiatives in stepwise plasma quality, safety, and volume enhancement; local small-scale synthesis of virus-safe clotting factors and immunoglobulins; and advancement of industrial plasma fractionation in collaboration with the WHO. Hence, such government initiatives are likely to increase the awareness and demand for plasma protein therapeutics, thereby boosting market growth over the forecast period.
Therefore, the studied market is predicted to grow over the forecast period due to the surge in plasma protein research and development and the incidence of autoimmune disorders, immune deficiency disorders, neurological disorders, and bleeding disorders. However, the stringent regulations for handling plasma protein products and the lack of proper reimbursement policies are the major drawbacks expected to hinder the market growth.
Plasma Protein Therapeutics Market Trends
Hemophilia Segment is Expected to Witness a Growth in the Plasma Protein Therapeutics Market Over the Forecast Period
Hemophilia is a rare genetic bleeding disorder that prevents normal blood clotting. The main symptom of this disorder is uncontrolled bleeding, which frequently occurs in various areas of the body. The amount of bleeding is determined by the severity of hemophilia. The segment is expected to grow in the future due to the increasing number of patients diagnosed with hemophilia. For instance, as per the article published in May 2022 by MedlinePlus, National Library of Medicine (NLM), Hemophilia A is the most prevalent type of the condition, with an incidence rate of 1 in 4,000 to 1 in 5,000 males worldwide born with this disorder, and Hemophilia B occurs in approximately 1 in 20,000 newborn males across the world. This prevalence of hemophilia among the target population is increasing the demand for advanced plasma protein therapeutics. As fresh frozen plasma (FFP) is one of the most commonly available for the treatment of hemophilia A and B in some countries, this is expected to drive the growth of the hemophilia segment.
Moreover, the increasing research & development (R&D) of new therapeutics and company activities are expected to boost segment growth over the forecast period. For instance, in July 2021, Sanofi presented Clinical data and new research from Sanofi's rare blood disorders portfolio of marketed and investigational therapies for people with hemophilia, immune thrombocytopenia (ITP) and acquired thrombotic thrombocytopenic purpura (aTTP) at the International Society on Thrombosis and Haemostasis (ISTH) 2021 Virtual Congress. In addition, in December 2021, Pfizer Inc. and Sangamo Therapeutics, Inc., a genomic medicines company, published an updated follow-up data from the Phase 1/2 Alta study of giroctocogene fitelparvovec, investigational gene therapy for patients with moderately severe to severe hemophilia A. Thus, increasing product development in the segment is anticipated to drive market growth over the forecast period.
Additionally, the rise in leukemia cases leads to the demand for plasma transfusion and therapy. Doctors prescribe platelet transfusions to people with leukemia who have low platelet counts. As per the American Cancer Society 2022 update, 35,810 males and 24,840 females were affected with leukemia.
Hence, due to the rise in hemophilia diseases, and the increase in research & development for hemophilia therapy, the hemophilia segment is expected to have significant growth over the forecast period.
North America is Expected to Witness a Growth in the Plasma Protein Therapeutics Market Over the Forecast Period
North America is expected to witness growth in the overall plasma protein therapeutics market throughout the forecast period owing to the increasing prevalence and incidence of autoimmune and neurological diseases and a rise in research & development in plasma protein. Moreover, the well-established healthcare infrastructure-focused market players on R&D for plasma protein therapeutics, coupled with recent product launches and the rising burden of autoimmune disorders, are primary growth factors for the market in the United States. For instance, as per the CDC November 2021 update, in the United States, 24% of all adults, or 58.5 million people, have arthritis. It is a leading cause of work disability, with annual costs for medical care and lost earnings of USD 303.5 billion. In fact, among chronic diseases in North America, arthritis causes more disability than any other condition, including heart disease, diabetes, and back or spine problems.
Furthermore, as per the October 2021 update from CDC, by 2040, an estimated 78.4 million adults aged 18 years and older are likely to be affected with doctor-diagnosed arthritis. Platelet-rich plasma therapy or PRP therapy, or autologous conditioned plasma (ACP) therapy, attempts to take advantage of the blood's natural healing properties to repair damaged cartilage, tendons, ligaments, muscles, or even bone. The therapy is currently used to treat arthritis. Hence, as per the estimates mentioned above, the growing arthritis cases in the United States are anticipated to create opportunities for advanced plasma protein therapies, driving the overall market growth in the country.
Additionally, product launches, collaborations, mergers, and acquisitions in the field of plasma protein therapeutics are likely to boost market growth over the forecast period. For instance, in October 2022, Grifols agreed with Canadian Blood Services to accelerate self-sufficiency in immunoglobulins for Canada. Under the 15-year agreement, the company is likely to provide an additional 2.4 million grams of Ig annually for Canadian patients and Canadian Blood Services with renewal options and pricing in line with Western market values and subject to periodic reviews. Hence, such collaborations and agreements with companies are likely to increase product availability in the studied region, thereby boosting market growth over the forecast period.
Therefore, due to the rise in blood-related disorders, increasing prevalence and incidence of autoimmune and neurological diseases, and research and development in plasma protein, the North American region is expected to witness substantial growth over the forecast period.
Plasma Protein Therapeutics Industry Overview
In the current scenario, strategies by the market players are increasing, fueling the plasma protein therapeutics market. The market is competitive in nature due to the heavy demand for products. The plasma protein therapeutics market is moderately competitive and consists of several major players. Some companies currently dominating the market are Takeda Pharmaceutical Company Limited, Octapharma USA Inc., Biotest UK, Baxter, Grifols, S.A., and CSL, among others.
Plasma Protein Therapeutics Market Leaders
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Octapharma USA Inc.
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Takeda Pharmaceutical Company Limited
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Biotest UK
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Grifols, S.A.
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CSL Limited
*Disclaimer: Major Players sorted in no particular order
Plasma Protein Therapeutics Market News
- October 2022: Grifols inaugurated its new state-of-the-art manufacturing plant in Ireland to meet the growing global demand for plasma medicines. Grifols' Dublin manufacturing facility triples the annual filling capacity of its innovative, flexible container, ALBUTEIN FlexBag, to meet the rising demand for albumin, the most abundant plasma protein.
- March 2022: The U.S. Food and Drug Administration (FDA) cleared the new plasma collection system, Rika Plasma Donation System (Rika), developed by Terumo Blood and Cell Technologies (Terumo BCT), a medical technology company. Rika is a next-generation automated technology focused on the experience of plasma center employees and donors.
Plasma Protein Therapeutics Market Report - Table of Contents
1. INTRODUCTION
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Increasing Incidence of Autoimmune and Neurological Diseases
4.2.2 Rise in Research & Development in Plasma Protein
4.3 Market Restraints
4.3.1 Strict Regulations for the Handling of Plasma Protein Products
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION (Market Size by Value in USD million)
5.1 By Product
5.1.1 Immunoglobulin
5.1.2 Albumin
5.1.3 Plasma Derived Factor VIII
5.1.4 Other Products
5.2 By Application
5.2.1 Hemophilia
5.2.2 Idiopathic Thrombocytopenic Purpura
5.2.3 Primary Immunodeficiencies
5.2.4 Other Applications
5.3 Geography
5.3.1 North America
5.3.1.1 United States
5.3.1.2 Canada
5.3.1.3 Mexico
5.3.2 Europe
5.3.2.1 Germany
5.3.2.2 United Kingdom
5.3.2.3 France
5.3.2.4 Italy
5.3.2.5 Spain
5.3.2.6 Rest of Europe
5.3.3 Asia-Pacific
5.3.3.1 China
5.3.3.2 Japan
5.3.3.3 India
5.3.3.4 Australia
5.3.3.5 South Korea
5.3.3.6 Rest of Asia-Pacific
5.3.4 Middle East and Africa
5.3.4.1 GCC
5.3.4.2 South Africa
5.3.4.3 Rest of Middle-East and Africa
5.3.5 South America
5.3.5.1 Brazil
5.3.5.2 Argentina
5.3.5.3 Rest of South America
6. COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.1 Takeda Pharmaceutical Company Limited
6.1.2 Octapharma USA Inc.
6.1.3 Grifols, S.A.
6.1.4 CSL Limited
6.1.5 Biotest UK
6.1.6 Baxter
6.1.7 Taibang Biological Group Co., Ltd
6.1.8 Kedrion S.p.A
6.1.9 Bio Products Laboratory Ltd
6.1.10 ADMA Biologics, Inc.
6.1.11 Arthrex, Inc.
6.1.12 Johnson and Johnson (DePuy Synthes)
- *List Not Exhaustive
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
Plasma Protein Therapeutics Industry Segmentation
Plasma protein therapy treats distinct medical conditions, restoring missing or inadequate proteins found in plasma to allow their receivers to lead healthier and more productive lives. Patients who rely upon plasma protein therapies generally require regular infusions for their lives.
The Plasma Protein Therapeutics Market is Segmented by Product (Immunoglobulin, Albumin, Plasma Derived Factor Vlll, and Other Products), Application (Hemophilia, Idiopathic Thrombocytopenic Purpura, Primary Immunodeficiencies, and Other Applications), and Geography (North America (United States, Canada, and Mexico), Europe (Germany, United Kingdom, France, Italy, Spain, and Rest of Europe), Asia-Pacific (China, Japan, India, Australia, South Korea, and Rest of Asia-Pacific), Middle East and Africa (GCC, South Africa, and Rest of Middle East and Africa), and South America (Brazil, Argentina, and Rest of South America)). The report offers value (in USD million) for the above segments.
| By Product | |
| Immunoglobulin | |
| Albumin | |
| Plasma Derived Factor VIII | |
| Other Products |
| By Application | |
| Hemophilia | |
| Idiopathic Thrombocytopenic Purpura | |
| Primary Immunodeficiencies | |
| Other Applications |
| Geography | ||||||||
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Plasma Protein Therapeutics Market Research FAQs
How big is the Plasma Protein Therapeutics Market?
The Plasma Protein Therapeutics Market size is expected to reach USD 30.49 billion in 2024 and grow at a CAGR of 5.5% to reach USD 39.85 billion by 2029.
What is the current Plasma Protein Therapeutics Market size?
In 2024, the Plasma Protein Therapeutics Market size is expected to reach USD 30.49 billion.
Who are the key players in Plasma Protein Therapeutics Market?
Octapharma USA Inc., Takeda Pharmaceutical Company Limited, Biotest UK, Grifols, S.A. and CSL Limited are the major companies operating in the Plasma Protein Therapeutics Market.
Which is the fastest growing region in Plasma Protein Therapeutics Market?
Asia-Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in Plasma Protein Therapeutics Market?
In 2024, the North America accounts for the largest market share in Plasma Protein Therapeutics Market.
What years does this Plasma Protein Therapeutics Market cover, and what was the market size in 2023?
In 2023, the Plasma Protein Therapeutics Market size was estimated at USD 28.81 billion. The report covers the Plasma Protein Therapeutics Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Plasma Protein Therapeutics Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
Plasma Protein Therapeutics Industry Report
Statistics for the 2024 Plasma Protein Therapeutics market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Plasma Protein Therapeutics analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
