Oncology Based In-Vivo CRO Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Global Oncology Based In-Vivo Contract Research Organization (CRO) Market is segmented by Indication (Blood Cancer, Solid Tumors, and Other Indication), Model (Syngeneic, Xenograft, Patient Derived Xenograft (PDX)), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (USD million) for the above segments.

Oncology Based In-Vivo CRO Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Oncology Based In-Vivo CRO Market Size

Oncology Based In-Vivo CRO Market Summary
Study Period 2019 - 2030
Base Year For Estimation 2024
Forecast Data Period 2025 - 2030
Historical Data Period 2019 - 2023
CAGR 7.30 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Oncology Based In-Vivo CRO Market Major Players

*Disclaimer: Major Players sorted in no particular order

Compare market size and growth of Oncology Based In-Vivo CRO Market with other markets in Healthcare Industry

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Oncology Based In-Vivo CRO Market Analysis

The Oncology Based In-Vivo CRO Market is expected to register a CAGR of 7.3% during the forecast period.

The COVID-19 pandemic has affected the healthcare systems globally and also has had a significant impact on the Oncology Based In-Vivo CRO Market. However, initiatives such as grant approval for vaccine production are expected to increase the market growth. For instance, in September 2022, the Gastro-Intestinal Research Foundation (GIRF) in Chicago granted Elicio Therapeutics a USD 2.8 million grant to fund research for two therapeutic cancer vaccines. ELI-007 is being developed to target BRAF gene mutations, whereas ELI-008 is being designed to target p53 hotspot mutations in solid tumors such as colorectal cancer, melanoma, and non-small cell lung cancer (NSCLC). Thus, the COVID-19 pandemic has impacted the oncology-based In-Vivo CRO market. However, the initiatives by key market players are expected to increase market growth during the forecast period.

The factors driving the market growth include increasing patient assistance programs (PAPs), increasing government initiatives for cancer awareness, the rising prevalence of cancer worldwide, vital R&D initiatives from key players, and the increasing demand for personalized medicine. According to the Globocan 2021 fact sheet, an estimated 19,292,789 new cancer cases were diagnosed worldwide, with nearly 9,958,133 deaths from cancer globally. According to estimates from the International Agency for Research on Cancer (IARC), by 2040, the global burden of cancers is expected to grow to 27.5 million new cancer cases and 16.3 million deaths worldwide. The high disease burden fuels the demand for outsourcing R&D activities for effective drug development/treatment. Thus, the increasing incidence of cancer cases is expected to drive the need for advanced cancer therapies to treat patients effectively. The dendritic cell (DC) vaccine can be achieved by the in vitro culture of DC (patient's autologous dendritic cell) and tumor-associated antigen. The low toxicity of DC vaccines in clinical trials makes it possible to use optimistic predictions of their applicability in broader clinical practice, thereby increasing their adaptability. For instance, in December 2021, researchers at Moffitt Cancer Center are working to develop a dendritic cell vaccine targeting HER3, a protein involved in the growth and spread of many different cancer types, including bladder, breast, lung adenocarcinoma, prostate, and stomach.

Similarly, in November 2021, Bioanalytical Systems, Inc. launched its new contract research service brand, Inotiv. Inotiv started representing the union of the company's Seventh Wave Laboratories & Smithers Avanza Toxicology Services, working in vivo toxicology, pharmacology, bioanalysis, drug metabolism, and pharmacokinetic solutions. Thus, given the factors above, the oncology based in-vivo CRO market is expected to witness tremendous growth over the forecast period.

However, the availability of alternatives and quality issues with CRO hamper the market's growth.

Oncology Based In-Vivo CRO Industry Overview

The oncology-based In-Vivo CRO market is moderately competitive and consists of several major players. In terms of market share, few of the major players have been currently dominating the market. And some prominent players have been vigorously making acquisitions and joint ventures with other companies to consolidate their market positions worldwide. Some companies currently dominating the market are Crown Bioscience Inc., Charles River Laboratories Inc., ICON PLC, Taconic Biosciences Inc., Covance Inc., Eurofins Scientific, EVOTEC, The Jackson Laboratory, Wuxi AppTec. and MI Bioresearch Inc.

Oncology Based In-Vivo CRO Market Leaders

  1. Crown Bioscience Inc.

  2. Charles River Laboratories, Inc.

  3. ICON plc

  4. Taconic Biosciences, Inc.

  5. Covance Inc.

  6. *Disclaimer: Major Players sorted in no particular order
Oncology Based In-Vivo CRO Market Concentration
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Oncology Based In-Vivo CRO Market News

  • In October 2022, Moderna, Inc., and Merck reported that Merck had exercised its option to develop and commercialize personalized cancer vaccine (PCV) jointly mRNA-4157/V940 under the terms of its existing Collaboration and License Agreement.
  • In March 2022, eTheRNA immunotherapies introduced a new Lipid Nanoparticle (LNP) formulation development and production service to support the discovery and early pre-clinical development of RNA-based therapeutics and vaccines.

Oncology Based In-Vivo CRO Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Rising incidence of Cancer Globally
    • 4.2.2 Increasing Initiatives by Market Players
  • 4.3 Market Restraints
    • 4.3.1 Availability of Alternatives and Quality issues with CRO
  • 4.4 Porter's Five Force Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Indication
    • 5.1.1 Blood Cancer
    • 5.1.2 Solid Tumors
    • 5.1.3 Other Indications
  • 5.2 By Model
    • 5.2.1 Syngeneic
    • 5.2.2 Xenograft
    • 5.2.3 Patient Derived Xenograft (PDX)
  • 5.3 Geography
    • 5.3.1 North America
    • 5.3.1.1 United States
    • 5.3.1.2 Canada
    • 5.3.1.3 Mexico
    • 5.3.2 Europe
    • 5.3.2.1 Germany
    • 5.3.2.2 United Kingdom
    • 5.3.2.3 France
    • 5.3.2.4 Italy
    • 5.3.2.5 Spain
    • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
    • 5.3.3.1 China
    • 5.3.3.2 Japan
    • 5.3.3.3 India
    • 5.3.3.4 Australia
    • 5.3.3.5 South Korea
    • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle East & Africa
    • 5.3.4.1 GCC
    • 5.3.4.2 South Africa
    • 5.3.4.3 Rest of Middle East & Africa
    • 5.3.5 South America
    • 5.3.5.1 Brazil
    • 5.3.5.2 Argentina
    • 5.3.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Champions Oncology Inc.
    • 6.1.2 Charles River Laboratory Inc.
    • 6.1.3 Crown Bioscience Inc.
    • 6.1.4 Eurofins Scientific
    • 6.1.5 EVOTEC
    • 6.1.6 ICON Plc
    • 6.1.7 Labcorp Drug Development (Laboratory Corporation of America Holdings)
    • 6.1.8 Living Tumor Laboratory
    • 6.1.9 Taconic Biosciences Inc.
    • 6.1.10 The Jackson Laboratory
    • 6.1.11 Wuxi AppTec.
    • 6.1.12 XenTech
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

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Oncology Based In-Vivo CRO Industry Segmentation

As per the report's scope, the oncology-based In-Vivo CRO provides preclinical drug development, testing, and infection diagnosis research in oncology. The demand for research organizations in the In-Vivo contract has been growing as pharmaceutical companies have been increasing their pipeline of drugs to create and produce new molecules to retain substantial benefits and patent products in the marketplace. The Oncology Based In-Vivo CRO Market is segmented by Indication (Blood Cancer, Solid Tumors, and Other Indication), Model (Syngeneic, Xenograft, Patient Derived Xenograft (PDX)), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Indication Blood Cancer
Solid Tumors
Other Indications
By Model Syngeneic
Xenograft
Patient Derived Xenograft (PDX)
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East & Africa GCC
South Africa
Rest of Middle East & Africa
South America Brazil
Argentina
Rest of South America
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Oncology Based In-Vivo CRO Market Research FAQs

What is the current Oncology Based In-Vivo CRO Market size?

The Oncology Based In-Vivo CRO Market is projected to register a CAGR of 7.3% during the forecast period (2025-2030)

Who are the key players in Oncology Based In-Vivo CRO Market?

Crown Bioscience Inc., Charles River Laboratories, Inc., ICON plc, Taconic Biosciences, Inc. and Covance Inc. are the major companies operating in the Oncology Based In-Vivo CRO Market.

Which is the fastest growing region in Oncology Based In-Vivo CRO Market?

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Oncology Based In-Vivo CRO Market?

In 2025, the North America accounts for the largest market share in Oncology Based In-Vivo CRO Market.

What years does this Oncology Based In-Vivo CRO Market cover?

The report covers the Oncology Based In-Vivo CRO Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Oncology Based In-Vivo CRO Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Europe Ablation Devices Industry Report

Statistics for the 2025 Oncology Based In-Vivo CRO market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Oncology Based In-Vivo CRO analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.