Market Trends of North America Glucagon-like Peptide-1 Agonists Industry
Liraglutide Segment holds the highest market share in the North American Glucagon-like Peptide-1 (GLP-1) Agonists Market in the current year
Liraglutide drug holds the highest market share of about 42.6% in the North American Glucagon-like Peptide-1 (GLP-1) Agonists Market in the current year.
GLP1RAs are available internationally and are recommended for use when treatment escalation for type 2 diabetes is required after metformin and lifestyle management. They can be safely used with all other glucose-lowering therapies except vildagliptin. Liraglutide, sold under Victoza, is an anti-diabetic medication for treating type 2 diabetes, obesity, and chronic weight management.
Liraglutide controls high blood sugar levels alone or in combination with other medications. It is prescribed to people with type 2 diabetes. Liraglutide is also used to reduce the risk of heart attack, stroke, or death in people with type 2 diabetes and heart disease. It works by increasing insulin release in response to high blood sugar levels after a meal and decreasing the amount of sugar produced by the liver. GLP1RAs elicit greater weight reduction and are recommended over SLGT2 inhibitors when cerebrovascular disease other than heart failure or renal disease predominates.
To help make the therapy cost more manageable, the Victoza Instant Savings Card Program allows the patient to print the savings card for instant use. With this card, the patient pays not more than USD 25 per Victoza prescription fill, valid for two years. It is equivalent to 24 prescription refills. However, due to the increased efficacy of the exenatide and semaglutide and the risks associated with Liraglutide causing dose-dependent and treatment-duration-dependent thyroid C-cell tumors, it will face tough competition leading to a decline in sales during the forecast period.
United States held the highest market share in the North America Glucagon-like Peptide-1 (GLP-1) Agonists Market in the current year
United States held the highest market share of about 95% in the North American Glucagon-like Peptide-1 (GLP-1) Agonists Market in the current year.
In addition to lowering blood glucose levels to help treat type 2 diabetes, GLP-1 agonists are also used in weight loss and other metabolic health benefits. GLP-1 RAs can be taken alone or in combination with other treatments for type 2 diabetes to improve blood glucose management, i.e., time in range. In addition to lowering blood glucose, they benefit heart health by reducing the risk of heart attack, stroke, and heart-related death. It is important because people with type 2 diabetes are at substantially higher risk of heart disease than those without diabetes.
In August 2022, Novo Nordisk announced headline results from a phase 2 clinical trial with CagriSema, a once-weekly subcutaneous combination of semaglutide and a novel amylin analog, cagrilintide. The trial investigated the efficacy and safety of a fixed dose combination of CagriSema (2.4 mg semaglutide and 2.4 mg cagrilintide) compared to the individual components, all administered once weekly, in 92 people with type 2 diabetes and overweight.
Owing to the rising prevalence and factors above, the growth of the studied market is anticipated over the forecast period.
