Market Trends of Global Narcolepsy Therapeutics Industry
This section covers the major market trends shaping the Narcolepsy Therapeutics Market according to our research experts:
Central Nervous System Stimulants Segment is Expected to Hold a Major Share During the Forecast Period
The Central Nervous System Stimulants segment is expected to hold a major share of the market during the forecast period. According to an article published in CNS Drugs, titled "Recently Approved and Upcoming Treatments for Narcolepsy", in January 2021, treatments such as modafinil, armodafinil, and other central nervous stimulants for narcolepsy are aimed at improving wakefulness in patients with narcolepsy.
Rising research on central nervous system stimulants is expected to drive the growth of this segment. For instance, in December 2021, Harmony Biosciences Holdings, Inc., a pharmaceutical company dedicated to developing and commercializing innovative therapies for patients with rare neurological diseases, published a data analysis of CNS drugs that evaluated the time to onset of response to pitolisant for excessive daytime sleepiness (EDS) and cataplexy in adult narcolepsy patients. Such studies will lead to the development of novel central nervous system stimulants, thereby driving this segment's growth.
Furthermore, according to the study published in Sleep Medicine and the Evolution of Contemporary Sleep Pharmacotherapy, titled "Narcolepsy Treatment: Present and Future" in October 2021, the combination of modafinil with connexin-30 inhibitors is under development as this generates a stimulant effect within the central nervous system (CNS). The rise in the development of CNS stimulants for narcolepsy will lead to novel combinations of molecules coming into the market, thereby driving the market's growth.
In addition, according to the study published in Neurotherapeutics, titled "A practical guide to the pharmacological and behavioral therapy of Narcolepsy" in April 2021, modafinil, a CNS stimulant, has been approved by the Food and Drugs Administration and the European Medicines Agency (EMA) for adult narcolepsy patients and is regarded as a good therapy due to its low potential for addiction and mild adverse effects.
Therefore, owing to the advantages of CNS stimulants in the treatment of narcolepsy, this segment is expected to drive the market over the forecast period.
North America is Expected to Hold a Significant Share in the Market Over the Forecast Period
North America is expected to hold a major share in the market studied during the forecast period. This is owing to the growing demand for sleep disorder treatment in the United States and Canada. The increasing prevalence of narcoleptic disorders has increased awareness, and high healthcare spending is anticipated to drive the market. In addition, favorable reimbursement policies for therapeutic products, a strong clinical pipeline, and rising stress levels are the other factors anticipated to promote revenue growth.
According to the National Institute of Neurological Disorders and Stroke fact sheet updated in November 2021, narcolepsy affects anywhere between 135,000 and 200,000 people in the United States. However, since this ailment is frequently misdiagnosed, the figure could be much higher. The high prevalence of narcolepsy in developed countries such as the United States will lead to increased adoption of narcolepsy therapeutics, thereby driving market growth in this region.
Furthermore, according to the news published in September 2021, Stanford researchers have proved that once-nightly narcolepsy treatment is safe and effective as a phase 3 study demonstrated that an extended-release variant of sodium oxybate lowers daytime sleepiness and attacks muscle weakness in narcolepsy patients. The rising effectiveness of narcolepsy treatments in the United States will lead to increased adoption of these therapies, thereby driving the growth of this market in this region.
In addition, in December 2021, Wake Up Narcolepsy, the charity group, received USD 1 million in donations for neurological research illnesses such as narcolepsy. The rise in donations for the development of narcolepsy treatments in the United States is further expected to drive the growth of this market in this region in the future.
All these factors are anticipated to contribute to the regional market's growth in the forthcoming years.
