Market Trends of Global Myeloproliferative Disorders (MPD) Treatment Industry
This section covers the major market trends shaping the Myeloproliferative Disorders Treatment Market according to our research experts:
Myelofibrosis Segment is Expected to Witness Growth Over the Forecast Period
Myelofibrosis is a group of rare cancers of bone marrow in which the marrow is replaced by scar tissue and cannot make healthy blood cells. It is classified as a type of chronic leukemia and belongs to a group of blood disorders called myeloproliferative diseases. It is also called primary myelofibrosis, chronic idiopathic myelofibrosis, or myelosclerosis with myeloid metaplasia.
The increasing research work and rising incidence of myelofibrosis are the major factors propelling segment growth. For instance, as per the study titled, "Real-world survival of US patients with intermediate- to high-risk myelofibrosis: impact of ruxolitinib approval" published in October 2021, based on the population-based studies, the estimated incidence of primary myelofibrosis in the United States is approximately 0.3 per 100,000 person-years.
Similarly, as per the Leukaemia Foundation article published in June 2020, primary myelofibrosis is considered one of the rare chronic disorders, and around 1 per 100,000 population were diagnosed with primary myelofibrosis. It can occur at any age but is usually diagnosed later in life, between the ages of 60 and 70 years. It also reported that around 20.0% of people have no symptoms of primary myelofibrosis when they were first diagnosed. Furthermore, continuos drug launch for treating myelofibrosis is also anticipated to propel the segment growth. For instance, in May 2022, Active Biotech AB announced that the United States Food and Drug Administration (FDA) has granted tasquinimod Orphan Drug Designation for the treatment of myelofibrosis.
Therefore, owing to the above-mentioned factors the segment is anticipated to witness considerable growth over the forecast period.
North America Is Expected to Dominate the Myeloproliferative Disorders (MPD) Treatment Market Over the Forecast Period
North America is expected to dominate the overall myeloproliferative disorders (MPD) treatment market, over the forecast period. The growth is due to factors such as increasing cases of myeloproliferative disorders, rising research and development investments, and increasing research works for developing novel treatments for myeloproliferative disorders in the region. For instance, in September 2020, Bristol Myers Squibb Canada (BMS) announced that the Health Canada has approved INREBIC (fedratinib), a new once-daily oral medication used to treat adults with an enlarged spleen and associated symptoms caused by intermediate-2 or high-risk primary myelofibrosis, post-polycythemia vera myelofibrosis or post-essential thrombocythemia myelofibrosis. Thus, such instances may propel the growth of the region.
Key product launches, high concentration of market players or manufacturer's presence, and acquisition & partnerships among major players increasing R&D investments by key players in the United States, and rising research works are some of the factors driving the growth of the myeloproliferative disorders (MPD) treatment market in the country. For instance, as per the study titled, "Next Generation Therapeutics for the Treatment of Myelofibrosis" published in April 2021, currently non-Janus kinase (JAK) inhibitor-based therapies are being explored in pre-clinical and clinical settings. Although JAK inhibitors were approved for the treatment of myelofibrosis, it does not significantly impact disease progression and many patients are ineligible due to coexisting cytopenias. In addition, patients who are refractory to JAK inhibition also have a dismal survival. Therefore, in order to overcome such a scenario the research works are being conducted to combat the disorder with more efficacy.
Therefore, owing to the aforesaid factors the growth of the studied market is anticipated in the North America Region.
