Membrane Chromatography Market Size (2024 - 2029)

Membrane Chromatography Market Analysis

The Membrane Chromatography Market size is estimated at USD 0.3 billion in 2024, and is expected to reach USD 0.6 billion by 2029, growing at a CAGR of 16% during the forecast period (2024-2029).

Membrane chromatography is a well-established bioprocessing technology routinely used to capture large particles such as viruses and viral vectors and in polishing steps for removing DNA, host cell protein impurities (HCP), and viruses. The rising demand for biopharmaceuticals and increasing regulatory scrutiny on the cleaning validation of downstream purification processes are the major factors for the growth of this market. For instance, in December 2022, Shimadzu collaborated with the University Medical Center Göttingen, Germany, to develop new clinical laboratory methods using liquid chromatography-mass spectrometry for therapeutic drug monitoring (TDM) analysis. Thus, such collaborations are expected to fuel market growth during the forecast period.

Also, the pharmaceutical industry's growing research and development spending to develop advanced membrane chromatography systems and the adoption of such products across the pharmaceutical and biopharmaceutical industries is anticipated to increase, propelling market growth. For instance, Merck & Co. invested USD 30.5 billion in R&D during FY 2023, representing 50.8% of the total revenue. Notably, a significant portion of the funding is dedicated to partnerships and acquisitions, highlighting a focus on collaboration and accelerating drug development. Hence, rising R&D spending by pharma companies creates a surge in complex research, driving demand for membrane chromatography during the manufacturing process of drugs during the forecast period.

Moreover, the increase in R&D spending in the biopharmaceutical industry aided in the growth of the market. For example, according to the Pharmaceutical Industry and Global Health Facts and Figures 2022 report, the biopharmaceutical industry's annual research and development spending was 8.1 times greater than other industries. According to the same source, over USD 202 billion is estimated to be spent worldwide on biopharmaceutical research and development in 2024. Thus, with high R&D spending, the development of new drugs will increase, ultimately fueling the adoption of membrane chromatography systems and consumables across biopharmaceutical industries boosting market growth.

Thus, the demand for membrane chromatography technologies is propelled by the development of new drugs, a growing need for high purity, technological advancements, and an emphasis on efficient upstream processing across the biopharmaceutical industry. However, the limited use of membrane chromatography in large-scale manufacturing is expected to restrain the growth of the market during the forecast period.

Membrane Chromatography Industry Segmentation

As per the scope, membrane chromatography is a technique that combines the principles of membrane filtration and chromatography for separating biomolecules. It utilizes a microfiltration membrane containing pores with chromatography ligands attached to the inner surface.

The membrane chromatography market is segmented by product, technique, and geography. By product, the market is segmented into capsules and cartridges, syringe filters, membrane filters, filter plates, spin columns, and other consumables and accessories. By technique, the market is segmented into ion exchange membrane chromatography, affinity membrane chromatography, and hydrophobic interaction membrane chromatography (HIMC). By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD) for the above segments.