Market Trends of Liver Diseases Therapeutics Industry
This section covers the major market trends shaping the Liver Diseases Therapeutics Market according to our research experts:
The Anti Viral Drugs Segment is Expected to Dominate the Market During the Forecast Period
Because more people are getting liver diseases and drinking more alcohol, the need for medicines to treat liver diseases has grown a lot.
Antiviral drugs are a type of medicine used to treat hepatitis. They work by lowering the amount of HBV (hepatitis B virus) in the body and lowering the risk of getting cirrhosis and hepatocellular cancer.Some of the FDA-approved drugs include Mavyret, Zepatier, and Vosevi. These drugs have been widely used for many years. They are safe and effective, especially for patients with signs and symptoms of moderate-to-severe liver impairment or other serious liver problems.
The high incidence of virus-infected liver diseases, including hepatitis, and the efficacy of antiviral treatment are the major factors contributing to the growth of this segment in the studied market. Chronic hepatitis B virus (HBV) infection is still a serious public health concern globally because it can cause cirrhosis and hepatocellular carcinoma (HCC), which increase human mortality and morbidity. Antiviral drugs are often taken to suppress the hepatitis B virus and long-term complications associated with hepatitis B, including liver disease and impairment. As per the study published in the May 2021 issue of BMC Infectious Diseases, the direct-acting antiviral (DAA) drug treatment demonstrated a positive prognostic factor for liver function improvement in HCV (hepatitis C virus) patients. Furthermore, the research published in the August 2022 issue of BMC Gastroenterology demonstrated the effectiveness of antiviral treatment in HBeAg-negative chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase (ALT).
Therefore, the market for antiviral drugs has a significant market share and is anticipated to retain its dominance during the forecast period due to the rising incidence of virally-infected liver diseases and expanding research indicating the effectiveness of antiviral medication therapy.
North America is Expected to Dominate the Liver Disease Therapeutics Market
North America is the biggest market because that is where most clinical trial studies are done by research and academic institutions.Changes in lifestyles, like drinking more alcohol and eating less healthily, have also made liver disease more common.Over the next few years, the regional market is expected to grow because patients are becoming more aware of their health and because new products are being made to meet unmet medical needs.
There has been an increase in the incidence of liver diseases in the region. According to the Centers for Disease Control and Prevention, as of January 2023, 4.5 million adults were diagnosed with liver disease in the United States. Further, as per the same source, alcohol consumption is also very high in the country, which is one of the major factors responsible for the increase in the burden of liver disease, and about 25.1% of adults age 18 and older had approximately one heavy drinking day (five or more drinks for men and four or more drinks for women) in the previous years. Hence, the burden of liver diseases in the country is expected to increase over the years, which is anticipated to have a positive impact on the market.
Therefore, due to the rising prevalence of liver diseases, the management of liver diseases has evolved rapidly. To cater to the significant unmet needs in the market, players are focusing on research and development with potential candidates, primarily related to preventing liver disease progression and reducing anticipated liver morbidity and mortality. For instance, in December 2022, Altimmune, Inc. announced positive topline results from its 24-week (12-week extension) trial of Pemvidutide for non-alcoholic fatty liver disease, showing the potential to dramatically lower liver fat content and liver inflammation. Moreover, in January 2022, Madrigal Pharmaceuticals, Inc. announced positive topline clinical data from the placebo-controlled, double-blind version of its phase 3 MAESTRO-NAFLD (Non-Alcoholic Fatty Liver Disease) safety study of Resmetirom.
Hence, the growing prevalence rates of liver diseases and the introduction of new products targeting unmet medical needs are expected to drive regional market growth over the forecast period.
