Global Hydrophobic Interaction Chromatography Market Size (2024 - 2029)

The hydrophobic interaction chromatography market is projected to expand significantly over the forecast period, driven by increased demand in vaccine production and the development of monoclonal antibodies for treating various diseases. The COVID-19 pandemic has notably influenced this growth, as pharmaceutical and biotech companies have relied on chromatography for vaccine manufacturing. Additionally, rising research and development investments in oncology and analytic techniques are contributing to the market's expansion. Despite these positive trends, challenges such as a shortage of skilled professionals and the presence of alternative chromatography methods may hinder the market's growth trajectory.

Market Size of Global Hydrophobic Interaction Chromatography Industry

Hydrophobic Interaction Chromatography Market Size
Study Period 2019 - 2029
Base Year For Estimation 2023
Forecast Data Period 2024 - 2029
CAGR 7.60 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

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*Disclaimer: Major Players sorted in no particular order

Hydrophobic Interaction Chromatography Market Analysis

The hydrophobic interaction chromatography market is expected to witness a CAGR of 7.6% during the forecast period.

The impact of the COVID-19 pandemic was significant on the studied market owing to the increased demand for vaccine production and manufacturing by various pharmaceutical and biotech companies worldwide, deploying chromatography, which ultimately impacted the market. For instance, a research article titled "Mechanistic Modeling for a Hydrophobic-Interaction Chromatography Process: Use in Vaccine Antigen Purification" was published in Bioprocessing International in September 2022 that proposed a model for the Industrial HIC process. Also, in December 2020, the Pfizer-BioNTech COVID-19 vaccine Comirnaty, one of the first vaccines to be made available under the emergency use authorization (EUA) for those 16 years of age and older was approved by the United States Food and Drug Administration. With the rising demand for vaccines for infectious and chronic diseases and increasing research studies, the demand for hydrophobic interaction chromatography is expected to grow. 

In addition, the growing demand for monoclonal antibodies and increasing research and development investment in oncology and analytic techniques are actively affecting the growth of the studied market.

According to the Globocan 2020 fact sheet, an estimated 19,292,789 new cancer cases were diagnosed worldwide, with nearly 9,958,133 deaths due to cancers, globally. Additionally, according to estimates from the International Agency for Research on Cancer (IARC), the global burden of cancers is expected to grow to 27.5 million new cancer cases worldwide by 2040. The increasing incidence of cancer cases is expected to drive the need for monoclonal antibodies and expedite research and development in oncology sector to develop a noval treatment, which uses hydrophobic interaction chromatography for the purification process and is ultimately projected to boost the market growth.

The growth is attributed to increasing demand for monoclonal antibodies in the treatment of many fatal diseases coupled with increasing launches and approvals by the key market players. For instance, in February 2022, a new monoclonal antibody, bebtelovimab received the United States Food and Drug Administration emergency use authorization (EUA) for the treatment of COVID-19 while maintaining activity against the omicron variant. Such developments are anticipated to boost the utility of chromatography which is projected to boost the market segment.

Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period. However, the lack of skilled professionals and the availability of other chromatography techniques are likely to impede the market growth.

Hydrophobic Interaction Chromatography Industry Segmentation

As per the scope of the report, hydrophobic interaction chromatography is the process of separating molecules based on their hydrophobic nature. This method is useful for the separation of proteins in complex mixtures. The report covers resins and columns that are used in hydrophobic interaction chromatography. The Hydrophobic Interaction Chromatography Market is Segmented by Product (Columns, Resins, and Buffer), Sample Type (Monoclonal Antibodies, Vaccines, and Others), End-User (Contract Research Organizations, Pharma and Biopharmaceutical Companies, and Others) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (in USD million) for the above segments.

By Products
Columns
Resins
Buffers
By Sample Type
Monoclonal Antibodies
Vaccines
Others
End-User
Contract Research Organizations
Pharma and Biopharmaceutical Companies
Others
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle-East and Africa
GCC
South Africa
Rest of Middle-East and Africa
South America
Brazil
Argentina
Rest of South America
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Global Hydrophobic Interaction Chromatography Market Size Summary

The hydrophobic interaction chromatography market is poised for significant growth, driven by the increasing demand for vaccine production and the rising prevalence of chronic diseases such as cancer. The COVID-19 pandemic underscored the importance of chromatography in vaccine development, with pharmaceutical and biotech companies leveraging these techniques to meet global health needs. This surge in demand is further fueled by the growing need for monoclonal antibodies, which are crucial in treating various diseases, including cancer. The market is also benefiting from advancements in research and development, particularly in oncology, where hydrophobic interaction chromatography plays a vital role in the purification processes. Despite challenges such as a shortage of skilled professionals and competition from other chromatography techniques, the market is expected to expand steadily over the forecast period.

North America is anticipated to lead the market, supported by a robust healthcare infrastructure, a high incidence of cancer, and substantial investments in research and development. The region's strong presence of industry players and heightened awareness of advanced technologies further bolster market growth. Key market players, including Bio-Rad Laboratories, Thermo Fisher Scientific, and Sartorius AG, are actively contributing to the market's expansion through technological innovations and strategic collaborations. These companies are focusing on developing novel antibody-drug conjugates and other advanced solutions to enhance the efficacy of cancer treatments. As the market continues to evolve, the fragmented nature of the industry, with numerous global and regional players, is expected to foster competitive dynamics, driving further advancements in hydrophobic interaction chromatography applications.

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Global Hydrophobic Interaction Chromatography Market Size - Table of Contents

  1. 1. MARKET DYNAMICS

    1. 1.1 Market Overview

    2. 1.2 Market Drivers

      1. 1.2.1 Growing Demand for Monoclonal Antibodies

      2. 1.2.2 Increasing Research and Development Investment in Oncology and Analytic Techniques

    3. 1.3 Market Restraints

      1. 1.3.1 Lack of Skilled Professionals

      2. 1.3.2 Availability of Other Chromatography Techniques

    4. 1.4 Porter's Five Force Analysis

      1. 1.4.1 Threat of New Entrants

      2. 1.4.2 Bargaining Power of Buyers/Consumers

      3. 1.4.3 Bargaining Power of Suppliers

      4. 1.4.4 Threat of Substitute Products

      5. 1.4.5 Intensity of Competitive Rivalry

  2. 2. MARKET SEGMENTATION (Market Size by Value- USD million)

    1. 2.1 By Products

      1. 2.1.1 Columns

      2. 2.1.2 Resins

      3. 2.1.3 Buffers

    2. 2.2 By Sample Type

      1. 2.2.1 Monoclonal Antibodies

      2. 2.2.2 Vaccines

      3. 2.2.3 Others

    3. 2.3 End-User

      1. 2.3.1 Contract Research Organizations

      2. 2.3.2 Pharma and Biopharmaceutical Companies

      3. 2.3.3 Others

    4. 2.4 Geography

      1. 2.4.1 North America

        1. 2.4.1.1 United States

        2. 2.4.1.2 Canada

        3. 2.4.1.3 Mexico

      2. 2.4.2 Europe

        1. 2.4.2.1 Germany

        2. 2.4.2.2 United Kingdom

        3. 2.4.2.3 France

        4. 2.4.2.4 Italy

        5. 2.4.2.5 Spain

        6. 2.4.2.6 Rest of Europe

      3. 2.4.3 Asia-Pacific

        1. 2.4.3.1 China

        2. 2.4.3.2 Japan

        3. 2.4.3.3 India

        4. 2.4.3.4 Australia

        5. 2.4.3.5 South Korea

        6. 2.4.3.6 Rest of Asia-Pacific

      4. 2.4.4 Middle-East and Africa

        1. 2.4.4.1 GCC

        2. 2.4.4.2 South Africa

        3. 2.4.4.3 Rest of Middle-East and Africa

      5. 2.4.5 South America

        1. 2.4.5.1 Brazil

        2. 2.4.5.2 Argentina

        3. 2.4.5.3 Rest of South America

Global Hydrophobic Interaction Chromatography Market Size FAQs

The Global Hydrophobic Interaction Chromatography Market is projected to register a CAGR of 7.60% during the forecast period (2024-2029)

Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Sartorius AG, Tosoh Bioscience GmbH and General Electric (GE Healthcare) are the major companies operating in the Global Hydrophobic Interaction Chromatography Market.

Hydrophobic Interaction Chromatography Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)