| Study Period | 2019 - 2030 |
| Base Year For Estimation | 2024 |
| Forecast Data Period | 2025 - 2030 |
| Historical Data Period | 2019 - 2023 |
| CAGR | 7.60 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Hydrophobic Interaction Chromatography Market Analysis
The Global Hydrophobic Interaction Chromatography Market is expected to register a CAGR of 7.6% during the forecast period.
The impact of the COVID-19 pandemic was significant on the studied market owing to the increased demand for vaccine production and manufacturing by various pharmaceutical and biotech companies worldwide, deploying chromatography, which ultimately impacted the market. For instance, a research article titled "Mechanistic Modeling for a Hydrophobic-Interaction Chromatography Process: Use in Vaccine Antigen Purification" was published in Bioprocessing International in September 2022 that proposed a model for the Industrial HIC process. Also, in December 2020, the Pfizer-BioNTech COVID-19 vaccine Comirnaty, one of the first vaccines to be made available under the emergency use authorization (EUA) for those 16 years of age and older was approved by the United States Food and Drug Administration. With the rising demand for vaccines for infectious and chronic diseases and increasing research studies, the demand for hydrophobic interaction chromatography is expected to grow.
In addition, the growing demand for monoclonal antibodies and increasing research and development investment in oncology and analytic techniques are actively affecting the growth of the studied market.
According to the Globocan 2020 fact sheet, an estimated 19,292,789 new cancer cases were diagnosed worldwide, with nearly 9,958,133 deaths due to cancers, globally. Additionally, according to estimates from the International Agency for Research on Cancer (IARC), the global burden of cancers is expected to grow to 27.5 million new cancer cases worldwide by 2040. The increasing incidence of cancer cases is expected to drive the need for monoclonal antibodies and expedite research and development in oncology sector to develop a noval treatment, which uses hydrophobic interaction chromatography for the purification process and is ultimately projected to boost the market growth.
The growth is attributed to increasing demand for monoclonal antibodies in the treatment of many fatal diseases coupled with increasing launches and approvals by the key market players. For instance, in February 2022, a new monoclonal antibody, bebtelovimab received the United States Food and Drug Administration emergency use authorization (EUA) for the treatment of COVID-19 while maintaining activity against the omicron variant. Such developments are anticipated to boost the utility of chromatography which is projected to boost the market segment.
Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period. However, the lack of skilled professionals and the availability of other chromatography techniques are likely to impede the market growth.
Hydrophobic Interaction Chromatography Market Trends
Monoclonal Antibodies Segment is Expected to Witness Growth Over The Forecast Period
Monoclonal antibodies are identical antibodies produced artificially through genetic engineering from parent cells. The monoclonal antibodies are used extensively in cancer treatment, bone marrow transplantation, and many other therapeutic applications. Hydrophobic interaction chromatography is widely used in purification of monoclonal antibodies.
According to The University of Texas MD Anderson Cancer Center January 2022 update, monoclonal antibodies are transforming how physicians treat cancer and other diseases, including COVID-19. These medications imitate the immune system's built-in defense against infection. Many cancer forms are treated using monoclonal antibodies. They can be used either alone or in conjunction with other cancer treatments, and they are administered to patients via an infusion. Depending on the antigen that each monoclonal antibody is targeting, it may function in single or several ways. Owing to the advantages of monoclonal bodies, its usage is projected to propel during the forecast period.
In addition, technological advancements, product launches, approval, along with partnerships by the key market players is likely to boost the segment growth. For instance, in March 2022, Sanofi and Seagen collaborated to create and market a variety of novel antibody-drug conjugates for three cancer targets. The advancements in the monoclonal antibodies are fueling the usage of hydrophobic interaction chromatography and propel the segment growth during the forecast period.
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North America is Expected to Dominate The Hydrophobic Interaction Chromatography Market Over The Forecast Period
North America is expected to dominate the market owing to factors such as the rising incidence of cancer, the strong presence of industry players in the region, better healthcare infrastructure, awareness among people and healthcare industry stakeholders about available technologies, and the increasing research and development investment in the region.
According to the American Cancer Society, Cancer Statistics 2022, 1,918,030 new cancer cases and 609,360 cancer deaths are predicted to occur in the United States in 2022. Also, according to the Canadian Cancer Statistics November 2021 report, an estimated 2 in 5 Canadians were likely to be diagnosed with cancer in their lifetime. It stated that an estimated 229,200 Canadians was predicted to be diagnosed with cancer in 2021. The high burden of cancer in the region is likely to boost the research and development activities to prepare monoclonal antibodies for its treatment which is projected to boost the utility of hydrophobic interaction chromatography in the region.
Factors such as increasing research and development in developing monoclonal antibodies for various applications in various diseases, especially cancer, coupled with technological advancements, are fueling market growth in the region during the forecast period. For instance, In August 2022, AstraZeneca and Daiichi Sankyo's Enhertu (trastuzumab deruxtecan) received the United States Food and Drug Administration approval for the treatment of adult patients with unresectable or metastatic non-small cell lung cancer (NSCLC). Enhertu is a specially developed HER2-directed antibody drug conjugate (ADC). Such advancements in the monoclonal antibodies for treatment of cancer is projected to boost the market during the forecast period.
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Hydrophobic Interaction Chromatography Industry Overview
The hydrophobic interaction chromatography market is fragmented in nature due to the presence of many companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international as well as local companies which hold the market shares and are well known. Some key market players are Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, General Electric, Sartorius AG, Tosoh Bioscience GmbH, KNAUER, Sepax Technologies, Inc., Merck KGaA., JNC Corporation, and Geno Technology Inc., USA among others.
Hydrophobic Interaction Chromatography Market Leaders
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Bio-Rad Laboratories, Inc.
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Thermo Fisher Scientific
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Sartorius AG
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Tosoh Bioscience GmbH
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General Electric (GE Healthcare)
- *Disclaimer: Major Players sorted in no particular order
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Hydrophobic Interaction Chromatography Market News
- In August 2022, Sunresin presented its most recent SEPLIFE products and solutions in the areas of microcarriers for cell culture and chromatography resins for downstream purification at the 2nd China International Vaccine Innovation Summit.
- In October 2022, VDO Biotech attended the Annual European Society of Gene & Cell Therapy in Edinburgh, England. VDO Biotech is a bioprocessing technology company that can offer affinity chromatography media for viral and plasmid purification.
Hydrophobic Interaction Chromatography Industry Segmentation
As per the scope of the report, hydrophobic interaction chromatography is the process of separating molecules based on their hydrophobic nature. This method is useful for the separation of proteins in complex mixtures. The report covers resins and columns that are used in hydrophobic interaction chromatography. The Hydrophobic Interaction Chromatography Market is Segmented by Product (Columns, Resins, and Buffer), Sample Type (Monoclonal Antibodies, Vaccines, and Others), End-User (Contract Research Organizations, Pharma and Biopharmaceutical Companies, and Others) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (in USD million) for the above segments.
| By Products | Columns | ||
| Resins | |||
| Buffers | |||
| By Sample Type | Monoclonal Antibodies | ||
| Vaccines | |||
| Others | |||
| End-User | Contract Research Organizations | ||
| Pharma and Biopharmaceutical Companies | |||
| Others | |||
| Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| Japan | |||
| India | |||
| Australia | |||
| South Korea | |||
| Rest of Asia-Pacific | |||
| Middle-East and Africa | GCC | ||
| South Africa | |||
| Rest of Middle-East and Africa | |||
| South America | Brazil | ||
| Argentina | |||
| Rest of South America | |||
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Hydrophobic Interaction Chromatography Market Research FAQs
What is the current Global Hydrophobic Interaction Chromatography Market size?
The Global Hydrophobic Interaction Chromatography Market is projected to register a CAGR of 7.6% during the forecast period (2025-2030)
Who are the key players in Global Hydrophobic Interaction Chromatography Market?
Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Sartorius AG, Tosoh Bioscience GmbH and General Electric (GE Healthcare) are the major companies operating in the Global Hydrophobic Interaction Chromatography Market.
Which is the fastest growing region in Global Hydrophobic Interaction Chromatography Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).
Which region has the biggest share in Global Hydrophobic Interaction Chromatography Market?
In 2025, the North America accounts for the largest market share in Global Hydrophobic Interaction Chromatography Market.
What years does this Global Hydrophobic Interaction Chromatography Market cover?
The report covers the Global Hydrophobic Interaction Chromatography Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Hydrophobic Interaction Chromatography Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
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Hydrophobic Interaction Chromatography Industry Report
Statistics for the 2025 Global Hydrophobic Interaction Chromatography market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Hydrophobic Interaction Chromatography analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
