Hormone Replacement Therapy Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Hormone Replacement Therapy Market Report is Segmented by Therapy (Estrogen Hormone Replacement, Growth Hormone Replacement, Thyroid Hormone Replacement, and Testosterone Replacement), Route of Administration (Oral, Parenteral, and Other Routes of Administration), Indication (Menopause, Hypothyroidism, Growth Hormone Deficiency, and Other Indications), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Market Size and Forecasts are Provided in Terms of Value (USD) for all the Above Segments.

Hormone Replacement Therapy Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Hormone Replacement Therapy Market Size

Hormone Replacement Therapy (HRT) Market Summry
Study Period 2019 - 2030
Market Size (2025) USD 25.97 Billion
Market Size (2030) USD 35.42 Billion
CAGR (2025 - 2030) 6.40 %
Fastest Growing Market Asia-Pacific
Largest Market North America
Market Concentration High

Major Players

Hormone Replacement Therapy Market Major Players

*Disclaimer: Major Players sorted in no particular order

Compare market size and growth of Global Hormone Replacement Therapy Market with other markets in Healthcare Industry

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Hormone Replacement Therapy Market Analysis

The Global Hormone Replacement Therapy Market size is estimated at USD 25.97 billion in 2025, and is expected to reach USD 35.42 billion by 2030, at a CAGR of 6.4% during the forecast period (2025-2030).

Specific factors that are positively affecting the hormone replacement therapy (HRT) market growth are increasing awareness of post-menopausal issues among women, the rise in drug development with novel delivery systems, and hormonal imbalance disorders such as acromegaly, hypothyroidism coupled with the rising geriatric population.

Increasing awareness of post-menopause issues is driving the hormone replacement therapy (HRT) market; as women become more informed, they seek tailored solutions for managing symptoms like vasomotor, mood swings, and osteoporosis, driving demand for HRT options. For instance, observed annually on October 28, World Menopause Day aims to highlight the complexities of menopause and its associated health risks. This initiative promotes open discussions between women and healthcare professionals, emphasizing the importance of resource sharing and enhancing the understanding of menopause and its management.

Similarly, the Government of Ireland rolled out Phase 2 of its Menopause Awareness campaign. The Department of Health amplified its efforts to foster open discussions and elevate awareness about menopause. This second phase introduced a television advertisement, complemented by outreach through national and local radio, newspapers, and magazines. Additionally, the campaign utilized out-of-home advertising on digital displays and bus shelters, along with targeted posts on social media. Budget 2023 eliminated VAT from hormone replacement therapy (HRT) to enhance equality of access. Thus, such campaigns increase awareness and education on menopause health issues and inform women about menopause symptoms and the benefits of HRT, thereby contributing to the market growth.

The increasing product launches by the market players and regulatory approval by the US FDA and other regulatory authorities are anticipated to spur market growth during the forecast period. For instance, in June 2023, Pfizer Inc. and OPKO Health Inc. revealed that the United States Food and Drug Administration (FDA) approved NGENLA (somatropin-gala). This once-weekly human growth hormone analog is indicated explicitly for pediatrics aged three years and older, addressing growth failures stemming from insufficient endogenous growth hormone secretion. Essentially, NGENLA (somatrogon-ghla) replenishes the body's deficient growth hormone. Thus, approval by regulatory authorities such as the FDA is expected to increase access to this drug and will likely propel the demand for this HRT, contributing to the segment's growth.

Thus, all factors above, such as increased awareness of menopause issues, the launch of awareness campaigns to educate women about menopause symptoms and available therapies, and the introduction of new products, are expected to propel the market's growth during the forecast period. However, the high cost of hormone replacement therapy and the risk of developing cancer from HRT are anticipated to hamper market growth globally.

Hormone Replacement Therapy Industry Overview

The market is moderately competitive, with few major players dominating the market globally. The key companies are Abbott Laboratories, Bayer AG, Merck KGaA, Novartis AG, and Pfizer Inc. Additionally, the key players are focused on global product portfolio expansion through acquisitions and collaborations with companies that complement their portfolios.

Hormone Replacement Therapy Market Leaders

  1. Abbott Laboratories

  2. Novartis AG

  3. Pfizer Inc.

  4. Merck KGaA

  5. Bayer AG

  6. *Disclaimer: Major Players sorted in no particular order
Hormone Replacement Therapy Market Concentration
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Hormone Replacement Therapy Market News

  • August 2024: Ascendis Pharma A/S revealed that the United States Food and Drug Administration (FDA) greenlit YORVIPATH (palopegteriparatide; formerly known as TransCon PTH) for treating adult hypoparathyroidism. YORVIPATH, a prodrug of parathyroid hormone (PTH[1-34]), is administered once daily and is crafted to ensure a steady release of PTH throughout the 24-hour dosing window.
  • February 2024: Knight Therapeutics Inc. launched BIJUVA (estradiol and progesterone) capsules in Canada. BIJUVA is designed to treat moderate to severe vasomotor symptoms (VMS) linked to menopause in women who have an intact uterus. Vasomotor symptoms, which include hot flashes and night sweats, impact 60% to 80% of women approaching menopause.

Global Hormone Replacement Therapy Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Awareness of Post-menopausal Issues among Women
    • 4.2.2 Rise in Drug Development with Novel Delivery Systems
    • 4.2.3 Hormonal Imbalance Disorders with Rising Geriatric Population
  • 4.3 Market Restraints
    • 4.3.1 High Cost of Hormone Replacement Therapy
    • 4.3.2 Substantial Risk of Cancer Associated with Hormone Replacement Therapy
  • 4.4 Porter's Five Force Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD)

  • 5.1 By Therapy
    • 5.1.1 Estrogen Hormone Replacement
    • 5.1.2 Growth Hormone Replacement
    • 5.1.3 Thyroid Hormone Replacement
    • 5.1.4 Testosterone Replacement
  • 5.2 By Route of Administration
    • 5.2.1 Oral
    • 5.2.2 Parenteral
    • 5.2.3 Other Routes of Administration
  • 5.3 By Indication
    • 5.3.1 Menopause
    • 5.3.2 Hypothyroidism
    • 5.3.3 Growth Hormone Deficiency
    • 5.3.4 Other Indications
  • 5.4 Geography
    • 5.4.1 North America
    • 5.4.1.1 United States
    • 5.4.1.2 Canada
    • 5.4.1.3 Mexico
    • 5.4.2 Europe
    • 5.4.2.1 Germany
    • 5.4.2.2 United Kingdom
    • 5.4.2.3 France
    • 5.4.2.4 Italy
    • 5.4.2.5 Spain
    • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
    • 5.4.3.1 China
    • 5.4.3.2 Japan
    • 5.4.3.3 India
    • 5.4.3.4 Australia
    • 5.4.3.5 South Korea
    • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 Middle East and Africa
    • 5.4.4.1 GCC
    • 5.4.4.2 South Africa
    • 5.4.4.3 Rest of Middle East and Africa
    • 5.4.5 South America
    • 5.4.5.1 Brazil
    • 5.4.5.2 Argentina
    • 5.4.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Abbott Laboratories
    • 6.1.2 Bayer AG
    • 6.1.3 Eli Lilly and Company
    • 6.1.4 F. Hoffmann-La Roche
    • 6.1.5 Merck KGaA
    • 6.1.6 Mylan NV
    • 6.1.7 Novartis AG
    • 6.1.8 Novo Nordisk AS
    • 6.1.9 Pfizer Inc.
    • 6.1.10 Amgen
    • 6.1.11 Genentech Inc.
    • 6.1.12 Abbvie Inc. (Allergan PLC)
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments
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Hormone Replacement Therapy Industry Segmentation

As per the scope of the report, hormone replacement therapy (HRT) is a treatment technique for replacing or replenishing hormones in the human body that are at inadequate levels than those required for the normal physiology of the human body. The most prominent application of HRT is in the treatment of symptom alleviation of menopause.

The hormone replacement therapy market is segmented by therapy, route of administration, indication, and geography. By therapy, the market is segmented as estrogen hormone replacement, growth hormone replacement, thyroid hormone replacement, and testosterone replacement. By route of administration, the market is segmented as oral, parenteral, and other routes of administration. By indication, the market is segmented as menopause, hypothyroidism, growth hormone deficiency, and other indications. By geography, the market is segmented as North America, Europe, Asia-Pacific, Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (USD) for all the above segments.

By Therapy Estrogen Hormone Replacement
Growth Hormone Replacement
Thyroid Hormone Replacement
Testosterone Replacement
By Route of Administration Oral
Parenteral
Other Routes of Administration
By Indication Menopause
Hypothyroidism
Growth Hormone Deficiency
Other Indications
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
South America Brazil
Argentina
Rest of South America
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Global Hormone Replacement Therapy Market Research Faqs

How big is the Global Hormone Replacement Therapy Market?

The Global Hormone Replacement Therapy Market size is expected to reach USD 25.97 billion in 2025 and grow at a CAGR of 6.40% to reach USD 35.42 billion by 2030.

What is the current Global Hormone Replacement Therapy Market size?

In 2025, the Global Hormone Replacement Therapy Market size is expected to reach USD 25.97 billion.

Who are the key players in Global Hormone Replacement Therapy Market?

Abbott Laboratories, Novartis AG, Pfizer Inc., Merck KGaA and Bayer AG are the major companies operating in the Global Hormone Replacement Therapy Market.

Which is the fastest growing region in Global Hormone Replacement Therapy Market?

Asia-Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Global Hormone Replacement Therapy Market?

In 2025, the North America accounts for the largest market share in Global Hormone Replacement Therapy Market.

What years does this Global Hormone Replacement Therapy Market cover, and what was the market size in 2024?

In 2024, the Global Hormone Replacement Therapy Market size was estimated at USD 24.31 billion. The report covers the Global Hormone Replacement Therapy Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Hormone Replacement Therapy Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Global Hormone Replacement Therapy Industry Report

Statistics for the 2025 Global Hormone Replacement Therapy market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Hormone Replacement Therapy analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.