| Study Period | 2019 - 2030 |
| Base Year For Estimation | 2024 |
| Market Size (2025) | USD 10.13 Billion |
| Market Size (2030) | USD 13.08 Billion |
| CAGR (2025 - 2030) | 5.23 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players*Disclaimer: Major Players sorted in no particular order |
Chromatography Instrumentations Market Analysis
The Global Chromatography Instrumentation Market size is estimated at USD 10.13 billion in 2025, and is expected to reach USD 13.08 billion by 2030, at a CAGR of 5.23% during the forecast period (2025-2030).
The COVID-19 pandemic is likely to have a slightly positive effect on the market. The COVID-19 pandemic is expected to have a positive effect on this segment. Since the pharmaceutical and bioindustry sectors have received a huge amount of attention recently, this is expected to positively aid in developing the gas chromatography market. In July 2020, an article was released in the 'Chromatography Today' magazine, which stated that the United States Air Force and researchers from the University of Michigan had collaborated to make modifications to an existing gas analysis system so that it could work like a breathalyzer that can analyze the breath and detect the chemical signature of acute respiratory distress syndrome (ARDS) in its very early stages, which is a precursor to most COVID-19 infections. Developments such as these are expected to positively aid the market growth.
Chromatography is used for quality control in the food industry by separating and analyzing additives, vitamins, preservatives, proteins, and amino acids. These factors have been the primary drivers of the growth of this market. Technological advancements in developing more accurate and efficient systems have also helped the market growth.
Moreover, according to the Centers for Disease Control updates from September 2022, in the United States, over 100 million adults suffer from diabetes or prediabetes, and this number has doubled over the last five years. Additionally, according to the Centre for Disease Control and Prevention (CDC) updates from July 2021, illnesses from mosquito, tick, and flea bites have tripled, and nine new vector-borne diseases were discovered. Thus, the increase in various illnesses and chronic diseases is expected to enhance the demand for downstream processing as chromatography columns are used to purify the product in downstream processing for drug development. Thereby, the market is expected to upsurge during the forecasted year.
In June 2020, Waters Corporation launched its new high-performance liquid chromatography (HPLC) - Waters Arc HPLC System. The company declared that the new liquid chromatography system could be used for routing testing in various end-use areas, such as the food & beverage industry, pharmaceuticals industry, and the academic and materials markets.
However, the high cost of HPLC instruments and the lack of skilled personnel for equipment handling are expected to hinder the market growth during the forecast period.
Chromatography Instrumentations Market Trends
Liquid Chromatography Systems are Expected to Dominate the Chromatography Instrumentation Market
Liquid chromatography (LC) is a separation technique in which the mobile phase is a liquid, where sample ions or molecules are dissolved. Conventional LC is commonly used in preparative scale work to purify and isolate some components of a mixture. Nowadays, liquid chromatography generally utilizes very small packing particles and relatively high pressure for analytical separations of solutions, detection & quantification, referred to as high-performance liquid chromatography (HPLC).
Companies in the market are focusing on launching advanced liquid chromatography systems and components. For instance, in November 2020, PerkinElmer Inc. launched a new HPLC, UHPLC, and next-generation software solution (LC 300TM platform and SimplicityChromTM software). Similarly, in March 2020, Scion Instruments launched new LC6000 series HPLC to their range of chromatography products.
The diverse qualitative and quantitative applications of LC along with mass spectroscopy in the pharmaceutical industry are reported in four key fields, which are synthetic organic chemistry, combinatorial library parallel synthesis, bioanalysis in support of ADME (absorption, distribution, metabolism, and excretion), proteomics, and also pharmaceutical research.
Additionally, in February 2021, Thermo Fisher Scientific launched its Vanquish Online 2D-Liquid Chromatography (LC) system, which offers versatility for multidimensional liquid chromatography. Moreover, in July 2022, Shimadzu launched its i-Series Plus integrated HPLC system that covers conventional to ultra-fast LC analysis. The launch coincides with the company's 50th anniversary of its presence in Europe.
As a result of the aforementioned main advantages, the short analysis time needed, and reliable results, liquid chromatography is extensively used for quality control purposes in the pharmaceutical and biotechnology industries. This will boost the growth of the segment in the coming years.
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North America is Expected to Dominate the Market Over the Forecast Period
North America accounts for the largest share of the chromatography instrumentation market due to growing government investments and funding for research. Additionally, the presence of major key participants in this region is expected to drive market growth. The countries also have developed well-structured health care systems. These systems also encourage research and development. These policies encourage global players to enter the United States and Canada. Due to their developed healthcare systems, these economies spend a high percentage of their gross domestic product on research and development. As a result, these countries enjoy the presence of many global market players and research laboratories, primarily using chromatography instrumentation. As demand is met by the presence of global players in the region, the market is further expected to increase.
In February 2022, The Federal Trade Commission approved Sartorius Stedim Biotech S.A.'s petition for prior approval of its acquisition of the Chromatography Equipment Business of Novasep Process SAS. Moreover, in May 2022, Agilent Technologies signed a collaboration agreement with APC Ltd., in which the companies committed to combining their technologies to provide unique workflows to customers that support automated process analysis via liquid chromatography (LC). Such acquisitions are expected to boost the growth of the market in the region.
Moreover, per the American Cancer Society statistic updated in January 2022, cancer continues to be the second most common cause of death in the United States, after heart disease. A total of 1.9 million new cancer cases and 609,360 deaths from cancer are expected to occur in the United States in 2022. The number is estimated to increase in the coming years due to the changing lifestyle of the people found in the region. Therefore, with the increasing prevalence of cancer, chromatography instrumentation is adopted to develop a vaccine for cancer; hence, the market is expected to grow in the region.
Therefore, owing to the above factors, the growth of the chromatography instrumentation market in North America is expected to drive over the forecast period.
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Chromatography Instrumentations Industry Overview
The market for chromatography instrumentation is moderately competitive, and key players are manufacturing a majority of chromatography instrumentation products. Market leaders with more funds for research and a better distribution system have established their position in the market. Moreover, Asia-pacific is witnessing an emergence of some small players due to the rise of awareness. This has also helped the market grow. Some of the major players are Agilent Technologies, Thermo Fisher Scientific, Merck KGaA, and Sartorious.
Chromatography Instrumentations Market Leaders
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Agilent Technologies
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Thermo Fisher Scientific
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Merck KGaA
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Sartorius AG
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Bio-Rad Laboratories
- *Disclaimer: Major Players sorted in no particular order
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Chromatography Instrumentations Market News
In June 2022, Agilent Technologies launched new liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS) quadrupole mass spectrometers that the company said will raise the level of built-in instrument intelligence and offer a higher level of instrument diagnostics to maximize system uptime for customers.
In June 2022, PerkinElmer, Inc. launched the GC 2400 Platform, an advanced, automated gas chromatography (GC), headspace sampler, and GC/mass spectrometry (GC/MS) solution designed to help lab teams simplify lab operations, drive precise results, and perform more flexible monitoring.
Chromatography Instrumentations Industry Segmentation
The chromatography instrumentations market is segmented by devices (chromatography systems (gas chromatography systems, liquid chromatography systems, fluid chromatography systems, and thin layer chromatography systems), consumables (columns, solvents/reagents/adsorbents, syringes/needles, and others) and accessories (column accessories, auto-sampler accessories, pumps, and other accessories)), application (agriculture pharmaceutical firms, clinical research organizations, environmental testing), geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major global regions. The report offers the value (in USD million) for the above segments.
| By Devices | By Chromatography Systems | Gas Chromatography Systems | |
| Liquid Chromatography Systems | |||
| Fluid Chromatography Systems | |||
| Thin Layer Chromatography Systems | |||
| By Consumables | Columns | ||
| Solvents/Reagents/Adsorbents | |||
| Syringes/Needles | |||
| Others | |||
| By Accessories | Column Accessories | ||
| Auto-Sampler Accessories | |||
| Pumps | |||
| Other Accessories | |||
| By Application | Agriculture | ||
| Pharmaceutical Firms | |||
| Clinical Research Organizations | |||
| Environmental Testing | |||
| Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| Japan | |||
| India | |||
| Australia | |||
| South Korea | |||
| Rest of Asia-Pacific | |||
| Middle-East and Africa | GCC | ||
| South Africa | |||
| Rest of Middle-East and Africa | |||
| South America | Brazil | ||
| Argentina | |||
| Rest of South America | |||
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Chromatography Instrumentations Market Research FAQs
How big is the Global Chromatography Instrumentation Market?
The Global Chromatography Instrumentation Market size is expected to reach USD 10.13 billion in 2025 and grow at a CAGR of 5.23% to reach USD 13.08 billion by 2030.
What is the current Global Chromatography Instrumentation Market size?
In 2025, the Global Chromatography Instrumentation Market size is expected to reach USD 10.13 billion.
Who are the key players in Global Chromatography Instrumentation Market?
Agilent Technologies, Thermo Fisher Scientific, Merck KGaA, Sartorius AG and Bio-Rad Laboratories are the major companies operating in the Global Chromatography Instrumentation Market.
Which is the fastest growing region in Global Chromatography Instrumentation Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).
Which region has the biggest share in Global Chromatography Instrumentation Market?
In 2025, the North America accounts for the largest market share in Global Chromatography Instrumentation Market.
What years does this Global Chromatography Instrumentation Market cover, and what was the market size in 2024?
In 2024, the Global Chromatography Instrumentation Market size was estimated at USD 9.60 billion. The report covers the Global Chromatography Instrumentation Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Chromatography Instrumentation Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
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Chromatography Instruments Industry Report
Statistics for the 2025 Global Chromatography Instrumentation market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Chromatography Instrumentation analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
