Market Trends of Gastroesophageal Reflux Disease Industry
H2 Receptor Blockers Segment is Expected to Witness Growth Over the Forecast Period
H2-receptor blockers also known as H2-receptor antagonists are used to treat duodenal ulcers and prevent their return. A few examples of available H2-receptor blockers are H2 antagonists including Tagamet (cimetidine), Axid (nizatidine), and Pepcid (famotidine). They are also used to treat disorders like Zollinger-Ellison disease, in which the stomach generates too much acid and gastric ulcers. Thus, the use of such drugs is prescribed by physicians for gastroesophageal reflux disease (GERD)-related diseases.
When choosing drugs for common disorders (such as heartburn, and acid reflux) patients generally go for the cost-effective generic ones. These H2 receptor blockers are economical which is a major factor driving the segment growth. For instance, the article published by SingleCare in April 2022 reported that H2 antagonists are commonly used for heartburn and are relatively cost-effective, especially when patients choose generic versions for treatment. Thus, such cost-effectiveness of the drugs is anticipated to drive the segment growth over the forecast period.
Additionally, product approvals and launch are the primary factors that is contributing to the growth of the market. For instance, in April 2021, Sanofi's Consumer Healthcare launched a new over-the-counter (OTC) medication Zantac 360°. The medication labeling denotes a new formula with the active ingredient of famotidine, a different histamine-2 (H2) blocker. Famotidine, also known under the trade name Pepcid and Pepcid AC is currently available in both brand-name and generic formulations. Thus, such developments are anticipated to boost segment growth over the forecast period.
Therefore, owing to the factors mentioned above such as the advantage of H2 antagonist, high availability of such drugs, and rising launches, the segment is anticipated to witness growth over the analysis period.
North America is Expected to Hold the Largest Market Share over the Forecast Period
North America is anticipated to witness growth over the forecast period due to the factors such as an increase in healthcare expenditure, increasing R&D, and the rising prevalence of GERD. Additionally, the rising geriatric population across the United States is the primary driver for the growth of the United States GERD market.
GERD is a common condition that affects many people globally, while the prevalence is higher in western countries, especially in the United States. An article on Nissen Fundoplication published in the National Library of Medicine in July 2022 mentioned that GERD has the highest prevalence in the United States, ranging from 18.1% to 27.8% of individuals. Such a high burden of disease in the country is anticipated to create growth opportunities for advanced and effective drugs in the nation, thereby, expanding the market growth.
Furthermore, the market players are currently focused on the development of advanced therapeutics for GERD. For instance, in May 2022, Phathom Pharmaceuticals, Inc., a biopharmaceutical company focused on developing and commercializing novel treatments for gastrointestinal diseases received Food and Drug Administration (FDA) acceptance for review of the company's New Drug Application (NDA) for vonoprazan as a treatment for adults for the healing of all grades of erosive esophagitis (EE) and relief of heartburn and maintenance of healing of all grades of EE and relief of heartburn.
In addition, in January 2022, the generic formulation of Dexilant has released as Dexlansoprazole Delayed Release 30mg and 60mg capsules, manufactured by the company 'TWI Pharmaceuticals USA'. Dexlansoprazole is a proton pump inhibitor used to treat heartburn caused by GERD and to heal erosive esophagitis. Such developments in the country are major driving factors of the market studied in the region.
Therefore, owing to the factors mentioned above, the market studied is anticipated to witness growth in the region.
