| Study Period | 2019 - 2030 |
| Market Size (2025) | USD 70.02 Billion |
| Market Size (2030) | USD 91.48 Billion |
| CAGR (2025 - 2030) | 5.49 % |
| Fastest Growing Market | Asia-Pacific |
| Largest Market | North America |
| Market Concentration | Low |
Major Players*Disclaimer: Major Players sorted in no particular order |
EPO Biomarkers Market Analysis
The EPO Biomarkers Market size is estimated at USD 70.02 billion in 2025, and is expected to reach USD 91.48 billion by 2030, at a CAGR of 5.49% during the forecast period (2025-2030).
Erythropoietin (EPO) biomarkers play a vital role in diagnosing, prognosis, and managing conditions related to erythropoiesis, such as anemia and chronic kidney disease. The increasing prevalence of chronic diseases, increasing research studies in diagnostic technologies, and surge in demand for personalized medicine contribute to the market growth during the forecast period. For instance, as per a study published by the Epidemiology of Chronic Disease and Prevention in July 2023, chronic kidney disease (CKD) affects 10%-15% of the worldwide population, and more than 2 million people globally received treatment with dialysis or kidney transplants to stay alive in 2022. Of these, 20% are treated in 100 low-income countries, which comprise half of the world's population.
Similarly, per data published by the International Society of Nephrology in August 2023, the median CKD prevalence in Eastern and Central Europe was 12.8%, ranging from 9.3% in Cyprus to 16.8% in Estonia in 2022. Thus, the increasing prevalence of chronic kidney diseases is anticipated to drive the demand for biomarkers, which play a crucial role in diagnosing and treating these diseases.
Moreover, as per the data published by the Minority HIV/AIDS Fund in November 2023, over 39 million people lived with HIV in 2022 around the globe. Certain regions of the globe are disproportionately affected by HIV. There were 20.8 million people with HIV in Eastern and Southern Africa, 4.8 million in Western and Central Africa, 6.5 million in Asia-Pacific, and 2.3 million in Western and Central Europe in 2022. With the growing needs of this patient population, the government and pharmaceutical industries are focused on investing more in developing EPO biomarkers, which positively affect market growth.
Factors such as favorable healthcare regulations in developed economies and increasing research and development in EPO biomarker technology are expected to drive market growth during the forecast period. For instance, in June 2022, the research team at Kyoto University unveiled the distinctive behaviors of erythropoietin (Epo)-producing cells. This discovery provides valuable insights into the mechanism behind renal anemia, a prevalent complication of chronic kidney disease resulting from the kidneys' inadequate production of EPO. Such studies are expected to expand the research and development activities related to EPO biomarkers to introduce innovative therapies, thereby surging its demand in the upcoming years.
Moreover, biomarkers offer valuable insights into disease pathogenesis and therapeutic efficacy, enabling personalized approaches and better clinical outcomes. As the demand for personalized medicine surges, the introduction of novel EPO biomarkers in the market significantly increases. For instance, as per a study published by Scientific Reports in September 2023, EPO levels were decreased in anemia of inflammation (AI) or anemia of unknown etiology (AUE) population while increased in bone marrow disease-associated anemia, suggesting its role in differentiating bone marrow disease in elderly anemic patients with unclear etiology. Thus, growing clinical studies highlighting the significance of EPO markers in diagnosing and treating various diseases are expected to open new growth avenues and expand its application in different therapeutic areas, thereby contributing to market growth.
Therefore, the market is anticipated to grow during the forecast period due to the increasing prevalence of chronic diseases, rise in research studies, and growing demand for personalized medicine. However, the limited availability of quality control testing laboratories and the risk of severe side effects may hinder the market's growth.
EPO Biomarkers Market Trends
The Cancer Segment by Application is Expected Witness Significant Growth During the Forecast Period
Erythropoietin (EPO) is a growth factor used to treat anemia caused by cancer or its treatment. The growing incidence of cancer is expected to be the key driver of the segment's growth during the forecast period. For instance, according to GLOBOCAN 2022 Statistics, approximately 20 million cancer cases were newly diagnosed worldwide in 2022, and by 2050, the number of cancer cases is predicted to increase to 35 million globally. The increasing incidence of cancer cases is anticipated to drive the need for the effective treatment of patients.
Cancer treatments such as chemotherapy and radiation therapy can lower the production of new blood cells, leading to anemia by decreasing red blood cell production. Some examples of erythropoietin used for the treatment of anemia caused by cancer treatment are epoetin alfa (Eprex), epoetin beta (NeoRecormon), epoetin zeta (Retacrit), and darbepoetin alfa (Aranesp).
For example, a study published by Highlights in Science, Engineering, and Technology in August 2024 concluded that recombinant human EPO (rhEPO) could effectively enhance the abnormal hematopoietic function of bone marrow damaged by chemotherapy. It was proved that rhEPO can significantly increase patients' hemoglobin (Hb) content and hematocrit (HCT) levels after chemotherapy and improve their tolerance. It further highlighted that it has fewer adverse reactions and is safer. Thus, the safety and positive clinical outcomes reported by EPO are anticipated to drive demand for the treatment of anemia caused by cancer treatment, thereby driving demand and segment growth.
Understand The Key Trends Shaping This Market
Download PDF
North America is Expected to Dominate the Market During the Forecast Period
North America is expected to witness healthy market growth during the forecast period. Factors such as the increasing prevalence of chronic diseases in countries of this region, coupled with the surge in clinical research related to EPO biomarkers and the strong presence of market players, are among some significant factors responsible for the market growth across the region.
The increasing incidence rate of HIV/AIDs among people in North America is a vital factor attributed to the growing usage of erythropoietin (EPO) biomarkers for effective diagnosis to boost the market's growth during the forecast period. For instance, the Centers for Disease Control and Prevention (CDC) data updated in May 2024, over 38,000 people received an HIV diagnosis. Men are most affected, making up almost 80% of diagnoses, with gay and bisexual men accounting for the majority in 2022. Similarly, as per the Public Health Agency of Canada's December 2023 publication, the new HIV diagnoses cases increased by 24.9% in 2022 compared to the previous year.
Additionally, the increasingly vulnerable aging population prone to chronic kidney diseases in the region is also contributing to the surging demand for early-stage diagnosis. For instance, according to the 2023 statistics published by the United Nations Population Fund, about 20% of the population in Canada was 65 years or older in 2023. Thus, a significant percentage of the aging population is expected to increase the burden of CKD, which is anticipated to increase new research and development, creating opportunities to advance EPO biomarkers.
Moreover, the region's continuous research and development to find the practical application of different EPO biomarkers in blood pressure, hypertension, and coronary artery disease is increasing. Thus, the ongoing research is poised to create more new opportunities for the studied market in the region. For instance, a study published by the World Journal of Cardiology in May 2023 examined the benefits of EPO in treating patients with cardiorenal syndrome (CRS). Recombinant human EPO (rhEPO) was a drug routinely prescribed to treat anemia in patients with end-stage renal disease (ESRD), and rhEPO treatment has been demonstrated to improve patients' life quality and survival. It is reasonable to assume that rhEPO treatment is useful for patients with CRS. Such studies highlight the clinical significance of EPO and broaden its practical application, which is anticipated to drive its demand across the region during the forecast period.
Therefore, owing to factors such as the increasing prevalence of chronic kidney diseases coupled with a surge in clinical studies, the significance of EPO markers in diagnosing and treating various diseases is anticipated for market growth in North America.
Get Analysis on Important Geographic Markets
Download PDF
EPO Biomarkers Industry Overview
The EPO biomarkers market is competitive and consists of several major players and smaller companies. With technological advancements and product innovations, mid-size to smaller companies are increasing their market presence globally. The competitive landscape includes analyzing several companies that hold most of the market shares, such as 3Sbio Group, Amgen Inc., Bio-Rad Laboratories Inc., F. Hoffmann-La Roche Ltd, and Kyowa Kirin Co. Ltd.
EPO Biomarkers Market Leaders
-
3Sbio Group
-
Amgen Inc.
-
Biocon
-
Bio-Rad Laboratories, Inc.
-
Eve Technologies
- *Disclaimer: Major Players sorted in no particular order
Need More Details on Market Players and Competitors?
Download PDF
EPO Biomarkers Market News
- March 2024: CSL Vifor, in partnership with Akebia Therapeutics Inc., received the United States Food and Drug Administration (FDA) approval for Vafseo (vadadustat), developed by Akebia. It is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor indicated to treat anemia caused by chronic kidney disease in adults who receive dialysis for at least three months.
- October 2023: Genexine, a clinical-stage Korean biopharmaceutical company in a joint venture with PT Kalbe Farma named KGbio, received approval from the Indonesian Food and Drug Authority (BPOM) for the treatment of chronic kidney disease-induced anemia in non-dialysis patients for novel long-acting erythropoietin, Epoetin alfa.
EPO Biomarkers Industry Segmentation
As per the scope of the report, EPO biomarkers are commonly used to treat end-stage renal (kidney) disease (ESRD) and anemia induced by multiple myeloma, cancer, and AIDS-associated anemia.
The market is segmented by type into erythropoietin alfa, erythropoietin beta, erythropoietin zeta, erythropoietin theta, and other types). By application, it is segmented into renal disorder, cancer, acquired immunodeficiency syndrome (AIDS), anemia of chronic inflammatory syndromes, and other applications. By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America.
The report also offers the market size and forecasts for 17 regional countries. The report offers market sizing and forecasts based on the value (USD) for the above segments.
| By Type | Erythropoietin Alfa | ||
| Erythropoietin Beta | |||
| Erythropoietin Zeta | |||
| Erythropoietin Theta | |||
| Other Types | |||
| By Application | Renal Disorder | ||
| Cancer | |||
| Acquired Immunodeficiency Sydnrome (AIDSs) | |||
| Anemia of Chronic Inflammatory Syndromes | |||
| Other Applications | |||
| Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| Japan | |||
| India | |||
| Australia | |||
| South Korea | |||
| Rest of Asia-Pacific | |||
| Middle East and Africa | GCC | ||
| South Africa | |||
| Rest of Middle East and Africa | |||
| South America | Brazil | ||
| Argentina | |||
| Rest of South America | |||
Need A Different Region or Segment?
Customize Now
EPO Biomarkers Market Research FAQs
How big is the EPO Biomarkers Market?
The EPO Biomarkers Market size is expected to reach USD 70.02 billion in 2025 and grow at a CAGR of 5.49% to reach USD 91.48 billion by 2030.
What is the current EPO Biomarkers Market size?
In 2025, the EPO Biomarkers Market size is expected to reach USD 70.02 billion.
Who are the key players in EPO Biomarkers Market?
3Sbio Group, Amgen Inc., Biocon, Bio-Rad Laboratories, Inc. and Eve Technologies are the major companies operating in the EPO Biomarkers Market.
Which is the fastest growing region in EPO Biomarkers Market?
Asia-Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).
Which region has the biggest share in EPO Biomarkers Market?
In 2025, the North America accounts for the largest market share in EPO Biomarkers Market.
What years does this EPO Biomarkers Market cover, and what was the market size in 2024?
In 2024, the EPO Biomarkers Market size was estimated at USD 66.18 billion. The report covers the EPO Biomarkers Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the EPO Biomarkers Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
EPO Biomarkers Industry Report
Statistics for the 2025 EPO Biomarkers market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. EPO Biomarkers analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
