Diphenhydramine Market Trends

Statistics for the 2023 & 2024 Diphenhydramine market trends, created by Mordor Intelligence™ Industry Reports. Diphenhydramine trend report includes a market forecast to 2029 and historical overview. Get a sample of this industry trends analysis as a free report PDF download.

Market Trends of Diphenhydramine Industry

Insomnia Segment is Estimated to Witness Significant Growth During the Forecast Period

  • Diphenhydramine is used to treat insomnia due to its sedative effects. It is available as an over-the-counter sleep aid formulation as it can induce drowsiness and help people fall asleep. The insomnia segment is expected to witness significant growth in the market owing to the growing numbers of individuals experiencing insomnia due to stress and lifestyle changes, the rising aging population, and the growing demand for diphenhydramine for treating sleep disorders.
  • The rising stress levels and mental health conditions like anxiety and depression contribute to higher rates of insomnia, boosting the need for treatments like diphenhydramine. In addition, older adults are more prone to sleep disorders, which is expected to boost the demand for diphenhydramine during the forecast period. For instance, according to 2024 data published in the Mental Health Statistics report, about 37.1% of women and 29.9% of men in the United Kingdom reported high anxiety during 2022-2023. The 2022 data published by the National Health Service reported a rise in the number of individuals with insomnia in England, from 7.87 million in 2021 to 8.32 million in 2022. The high number of populations suffering from anxiety leads to insomnia, which, in turn, is anticipated to bolster the demand for drugs that induce sleep, thereby contributing to segment growth.
  • The high prevalence of insomnia among the population is the key factor driving the demand for diphenhydramine to reduce sleep disorders; hence, it is anticipated to augment the segment’s growth. For instance, according to Sleep Statistics and Trends' May 2024 report, approximately 50% of insomnia cases in the United States arise from anxiety, depression, or psychological stress. Moreover, 30% of American adults experience insomnia, with one in ten enduring chronic insomnia nightly.
  • Similarly, as per an article published by Sleep Journal, in April 2024, about 123 million adults (16.8%) in the Americas were affected by insomnia disorder, comprising 73 million females (19.5%) and 50 million males (14.0%). Thus, the high prevalence of insomnia among the population and the demand for antihistamine drugs for sedating effects are anticipated to propel the market’s growth during the forecast period.
  • Furthermore, an article published by the Journal of Activity, Sedentary, and Sleep Behaviors in February 2024 highlighted insomnia as a significant health concern for older adults and is associated with a heightened morbidity rate and a decline in quality of life if left untreated. In addition, low education, chronic health conditions, smoking, being underweight, physical inactivity, and lack of exposure are some of the factors that are associated with the development of insomnia among the population.
  • Therefore, owing to the high prevalence of insomnia owing to increasing stress, anxiety, and depression among the population, the segment is anticipated to grow during the forecast period.
Diphenhydramine Market: Adults Experiencing Insomnia Symptoms (% in total population), United States, 2023

North America is Expected to Have a Significant Market Share During the Forecast Period

  • North America is anticipated to hold a significant share of the market during the forecast period owing to factors such as the increasing number of allergic people and growing government initiatives. For instance, according to the 2022 report from the Asthma and Allergy Foundation of America, around 25 metropolitan areas are under the high-risk category for allergy attacks.
  • Additionally, motion sickness is becoming more common among international travelers, which is driving the need for motion sickness medications. For instance, according to the 2023 data published by the National Travel and Tourism Office, an estimated 66.5 million tourists traveled internationally in the United States in 2023, an increase of 31% compared to 2022. Thus, the increasing number of people traveling across countries increases the risk of experiencing motion sickness, which, in turn, is expected to increase the demand for effective drugs that reduce the symptoms. This is further expected to fuel the demand for diphenhydramine to prevent and treat nausea, vomiting, and dizziness caused by motion sickness, hence propelling the market’s growth.
  • Furthermore, the high burden of insomnia among the population is expected to fuel market growth in North America during the forecast period. For instance, as per the Canadian Community Health Sleep Research Survey, in May 2022, more than 35% of Canadians found issues in falling asleep and staying asleep every night. Moreover, according to Sleep Statistics, updated in December 2022, between 10% and 30% of US adults struggle with chronic insomnia. Similarly, as per the Global Insomnia Statistics 2023 report, it was observed that half of the adults living in the United States experienced insomnia once a month or more in 2022. Thus, the high burden of the condition is expected to increase demand for novel antihistamine drugs, such as diphenhydramine, which cause drowsiness and induce sleep, which is anticipated to augment the market’s growth during the forecast period.
  • Moreover, with the rising pollution levels and changing environmental conditions, there has been an increase in the prevalence of allergies. This trend is propelling the demand for antihistamines, such as diphenhydramine, in the market. For instance, the data published by the Clean Air Fund in May 2024 stated that approximately 131 million Americans were exposed to unhealthy levels of ozone and particle pollution in 2024, marking an increase of 11.7 million from 2023. Hence, increased public awareness of allergy symptoms, coupled with the availability of effective over-the-counter treatments like diphenhydramine, is driving more consumers to purchase diphenhydramine, which is expected to bolster market growth during the forecast period.
  • Therefore, owing to the aforementioned factors, such as the high burden of insomnia, allergies, and motion sickness among the population, the market studied is anticipated to witness significant growth during the forecast period.
Diphenhydramine Market - Growth Rate by Region

Diphenhydramine Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)