Market Trends of CRISPR And CRISPR-associated (Cas) Genes Industry
Genome Engineering Segment is Anticipated to Witness a Growth in the Market Over the Forecast Period
- The market's genome engineering segment is likely to grow due to the increase in genomics research and development activities and funding. The CRISPR genome engineering system uses a nuclease, CRISPR-associated protein 9 (Cas9) that complexes with small guide RNAs (gRNAs) to cleave DNA in a sequence-specific manner upstream of the protospacer adjacent motif (PAM) in any genomic location.
- As per an article published in May 2022 in Frontiers, the introduction of specific mutations into mammalian cells to produce loss-of-function phenotypes is made simple by CRISPR technology. With the successful application of genome-wide CRISPR screening to discover host characteristics that limit viral infections, CRISPR became a potent tool for investigating the functional genomics of virus-host interactions.
- Moreover, various companies and academic and research institutions are using genome engineering techniques for the development of new therapies and treatments. Many researchers received funding to develop and establish genome engineering-related research, expected to drive segment growth over the forecast period. For instance, in December 2022, an assistant professor of biomedical engineering and computer science received USD 1.9 million in awards from the National Institutes of Health for genome sequencing research. The researcher also received USD 120,000 from Complete Genomics, a company that focuses on human genome sequencing.
- Furthermore, genomic engineering studies to understand cancer cells and their therapies gained a lot of attention, and that is expected to be a growth factor for the segment growth. For instance, as per the article published in October 2021 in BMC Journal, CRISPR/Cas9 can be utilized in the field of cancer research to modify genomes for the investigation of the mechanisms of carcinogenesis and development because genomic alterations in tumor cells cause cancer.
- Hence, due to the rise in research funding in genomic studies and the increase in research conducted to represent the efficacy of CRISPR in genomics, the segment studied is anticipated to witness growth over the forecast period.
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North America is Anticipated to Hold a Significant Growth in the CRISPR and CRISPR-associated (Cas) Genes Market Over the Forecast Period
- North America is expected to hold a significant market share in the CRISPR and CRISPR-Associated (Cas) genes market throughout the forecast period due to factors such as the high burden of cancer and other diseases, increasing genomics research and development activities and funding, and established healthcare infrastructure. For instance, in November 2021, CRISPR Therapeutics and ViaCyte publicized that Canada's medical agency Health Canada approved their clinical trial application for VCTX210, a CRISPR-edited stem cell therapy designed to treat type 1 diabetes. This is a milestone in medicine as it marks the first-ever gene-edited therapy for diabetes to approach the clinic.
- Furthermore, beneficial government initiatives and increased research partnerships are some drivers expected to increase market growth. Over the years, companies have collaborated with their peers to tap into certain niche segments of the CRISPR and CRISPR-Associated (Cas) genes market. For instance, in September 2022, the United States publicized new investments and resources to advance the National Biotechnology and Biomanufacturing initiative. As a part of this initiative, the Department of Health and Human Services is likely to invest USD 40 million to expand the role of biomanufacturing.
- Such rising funding activities by the government are expected to contribute to the market growth in this region. Thus, due to the rise in clinical studies associated with CRISPR and the increase in research funding, North America is anticipated to hold a significant market share over the forecast period.
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