Market Trends of Chronic Lymphocytic Leukemia Industry
This section covers the major market trends shaping the Chronic Lymphocytic Leukemia Market according to our research experts:
Parenteral Route of Administration Segment is Expected to Witness a Healthy Growth Over the Forecast Period
The parenteral route of the administration segment is expected to witness growth in recent years and is expected to do so over the forecast period. This dominance is due to their rapid absorption and onset of action, along with their availability in various routes such as intravenous, subcutaneous, intrathecal, or intramuscular routes according to the patient's need.
The data updated by the National Library of Medicine in February 2022, the parenteral route of administration can be done in three different ways such as intravenous injections, intramuscular and subcutaneous injections, among which intravenous injection is the common parental route of administration due to its benefit of bypassing the first-pass metabolism by the liver. Given their superficial location on the skin, peripheral veins provide easy access to the circulatory system and are often utilized in the parenteral administration of medications. Similarly, Ascendia Pharmaceuticals data updated in 2022 stated that the quickest and second-most popular method of drug delivery is parenteral formulation development for medications given by injection or infusion. Additionally, as per the Ascendia Pharmaceuticals data updated in 2022, a major benefit of parenteral administration is that it can provide a rapid onset of action and rapid absorption of the drug. Thus, such benefits and advantages of the parenteral route of administration of the segment is anticipated to grow over the forecast period.
Furthermore, more number of approved drugs available drugs for parenteral administration for the treatment of chronic lymphocytic leukemia (CLL) is one of the factors affecting segment growth. As per data medically reviewed by Drugs.com in April 2022, Bendamustine Hydrochloride Injection is indicated for treating patients with CLL with a recommended dose of 100 mg/m2 administered intravenously over 30 minutes on Days 1 and 2 of a 28-day cycle, up to 6 cycles. Thus, such instances are predicted to bolster market growth in the future.
Therefore, owing to the factors above, the studied segment is anticipated to show growth over the forecast period.
North America is expected to Hold a Significant Share in the Market During the Forecast Period
North America is anticipated to witness growth over the forecast period and dominate the market. The United States is leading the market due to high healthcare expenditure, research and development activities, and a rising prevalence of leukemia. Additionally, the rising geriatric population across the United States is the primary driver for the United States CLL market.
The data updated by the American Cancer Society in 2022, nearly 60,650 new cases of leukemia (all kinds) are estimated to be diagnosed in 2022, among which chronic lymphocytic leukemia (CLL) accounts for approximately 20,160 new cases. Additionally, as per the source mentioned above, about 1/4th of newly diagnosed cases of leukemia is CLL. The lifetime chance of developing CLL is approximately 1 in 175 (0.57%) for the average person. Most people with CLL are older individuals, typically of age 70 years old, when they receive a diagnosis. In addition, the data updated in February 2022 by HealthyPeople.gov shows that the population in the United States is aging unprecedently, and the population aged 65 or older is projected to reach 23.5% (98 million) by 2060 in the country. Thus, with the increasing geriatric population in the country, the risk of CLL is also rising. This is expected to generate demand for the availability of drugs and therapy for the disease for treatment. Hence, the studied market is anticipated to grow over the forecast period.
Moreover, the increasing research and development of various treatment options in the country are anticipated to drive market growth over the forecast period. For instance, in September 2021, Triplet therapy developed by researchers at the Dana-Farber Cancer Institute showed promise in a phase 2 study in chronic lymphocytic leukemia. As per the trial results, 86% of the trial participants demonstrated a significant response throughout the two-year study, and no Minimal Residual Disease (MRD) could be detected in these patients' bone marrow using sensitive cellular tests, which is a key predictor of survival without progression.
Therefore, owing to the factors mentioned above, North America is predicted to witness growth over the forecast period.
