Market Trends of Global Cell-free Protein Expression Industry
This section covers the major market trends shaping the Cell-free Protein Expression Market according to our research experts:
The E. Coli Lysate Segment of the Lysate Systems is Expected to be the Fastest Growing Segment Over the Forecast Period
E. coli lysates are the most commonly used among all available commercial cell-free Protein Expression Systems. E. coli lysates are devoid of endogenous genetic messages and have advantages, such as very high protein yield and tolerability to most additives. Furthermore, E. coli-based systems are being used in Recombinant Protein Expression techniques for the manufacture of various biological therapeutics and insulin. Continuous use has enabled research on interactions and tolerability of the byproducts of E. coli-based systems, and significant present scientific literature enables its rapid adoption by industries and academics.
In E. coli-based systems, codons used are different, with some being eukaryotic specific. Additionally, post-translational modifications are not possible, which in turn limit the system's usage in the synthesis of specific human therapeutics, impacting the Human Protein Expression Market. Significant advancements have been, however, made in order to address these problems. Therefore, the E. coli lysate sub-segment is expected to register a steady growth rate during the forecast period, owing to high adoption rates and recent developments.
North America Dominates the Market, and It is Expected to do Same in the Forecast Period
North America is found to hold a major share in the Cell-Free Protein Expression Market, and it is expected to show a similar trend over the forecast period, without significant fluctuations. The primary factors behind the large market size include the increasing prevalence of chronic diseases, such as cancer, aging population, growing demand for targeted and personalized medicine, the presence of major R&D facilities, and favorable government initiatives in the United States. There is a growing trend of cell-based and Synthetic Biology research in the US academia and biotechnology industries. In recent years, several government initiatives have been supplementing the growth of the Cell-Free Protein Expression Market in the United States, further bolstering the Synthetic Biology Industry.
In the North American region, the United States holds the largest market share due to factors such as the increasing burden of cancer cases in the country, which is anticipated to stimulate the demand for the Cell Free Expression Market.
According to Globocan 2020, an estimated 2,281,658 new cancer cases were diagnosed in 2020, and 612,390 cancer deaths were reported in the United States. The increasing demand and acceptance of cell-free protein expression in the treatment of diseases such as cancer, rare diseases, and other disorders are also driving the growth of the studied market in the region.
