Cell Based Immunotherapy Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Report Covers Cell Based Immunotherapy Market Trends and the Market is Segmented by Therapy (Autologous Cellular Immunotherapy, Chimeric Antigen Receptor (CAR) T-Cell Therapy, Dendritic Cell-Based Vaccine Therapy), Primary Indication (B-Cell Malignancies, Prostate Cancer, Renal Cell Carcinoma, Liver Cancer, and Others) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Market Provides the Value (in USD Million) for the Above-Mentioned Segments.

Cell Based Immunotherapy Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Cell-Based Immunotherapy Market Size

Cell-Based Immunotherapy Market Summary
Study Period 2019 - 2030
Base Year For Estimation 2024
Market Size (2025) USD 5.24 Billion
Market Size (2030) USD 10.54 Billion
CAGR (2025 - 2030) 14.98 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Cell-Based Immunotherapy Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Cell-Based Immunotherapy Market Analysis

The Global Cell Based Immunotherapy Market size is estimated at USD 5.24 billion in 2025, and is expected to reach USD 10.54 billion by 2030, at a CAGR of 14.98% during the forecast period (2025-2030).

The cell-based immunotherapy landscape is experiencing significant transformation through strategic collaborations and partnerships between biotechnology companies and research institutions. In May 2023, Janssen Biotech entered into a worldwide collaboration with Cellular Biomedicine Group Inc. (CBMG) to develop and commercialize next-generation chimeric antigen receptor (CAR) T-cell therapies, highlighting the industry's focus on expanding therapeutic options. These collaborations are complemented by substantial financial investments, as evidenced by CARGO Therapeutics securing USD 200 million in Series A financing in March 2023 to advance their next-generation CAR T-cell therapy pipeline.


The industry is witnessing remarkable advancements in personalized medicine approaches and manufacturing capabilities. Hospital Clínic Barcelona-IDIBAPS's development of CAR-T therapy ARI0002h in July 2023 demonstrated positive responses in all patients with multiple myeloma resistant to standard therapies, achieving complete remission in up to 67% of cases. This trend towards personalized treatment approaches is reshaping traditional therapeutic paradigms and driving innovation in manufacturing processes to ensure scalability and accessibility of these advanced cell-based immunotherapies.


Research institutions and pharmaceutical companies are increasingly focusing on expanding the application of cellular immunotherapy beyond hematological malignancies to solid tumors. In January 2023, LinKinVax announced a collaboration to conduct first-in-human Phase I/IIa clinical trials with CD40HVAc, a therapeutic vaccine candidate targeting head and neck cancer associated with human papillomavirus (HPV). This expansion into solid tumors represents a significant evolution in the field's therapeutic scope and potential market opportunities.


The market is characterized by a growing emphasis on improving manufacturing efficiency and reducing production costs to enhance accessibility. According to recent industry data from France, approximately 433,136 cancer cases were diagnosed in 2023, highlighting the significant potential patient population that could benefit from cellular immunotherapy. This large patient pool is driving investments in automated manufacturing processes and the establishment of regional manufacturing facilities to improve production efficiency and reduce time-to-patient delivery, making these therapies more accessible to a broader population. The role of cell-based immunotherapy manufacturers is crucial in this endeavor, as they strive to meet the increasing demand efficiently.

Segment Analysis: By Therapy

CAR T-Cell Therapy Segment in Cell-Based Immunotherapy Market

The CAR T-cell immunotherapy market segment dominates the global cell-based immunotherapy market, holding approximately 75% market share in 2024. This segment's commanding position is attributed to the increased adoption of CAR T-cell therapy due to its remarkable success rates in cancer treatment. The segment has demonstrated significant therapeutic outcomes in hematologic malignancies, which has stimulated its expansion into treating solid tumors. The approval of several CAR T-cell products across major markets, including the United States, European Union, and Asia-Pacific regions, has further strengthened its market position. Additionally, this segment is experiencing the fastest growth trajectory, with a projected growth rate of nearly 16% from 2024 to 2029, driven by continuous technological advancements, expanding therapeutic applications, and increasing investment in research and development activities.

Market Analysis of Global Cell Based Immunotherapy Market: Chart for By Therapy

Remaining Segments in Cell-Based Immunotherapy Market

The market's remaining segments include the dendritic cell cancer vaccine immunotherapy market and autologous cellular immunotherapy, each playing crucial roles in advancing cancer treatment options. Dendritic cell-based vaccine therapy has emerged as a promising approach, particularly in treating various types of cancers, including prostate cancer, ovarian cancer, and colorectal cancer. This segment benefits from its ability to induce specific immune responses and prolonged survival rates in cancer patients. Meanwhile, the autologous cellular immunotherapy segment has gained traction due to its personalized treatment approach and reduced risk of immune rejection. The segment's growth is supported by its applications in treating blood disorders, musculoskeletal conditions, and various types of cancers, with ongoing research expanding its potential applications.

Segment Analysis: By Primary Indication

B-cell Malignancies Segment in Cell-Based Immunotherapy Market

The B-cell malignancies segment dominates the global cellular immunotherapy market, accounting for approximately 65% market share in 2024. This substantial market position is primarily driven by the increasing adoption of CAR T-cell therapy and other innovative cell-based treatments specifically designed for various B-cell lymphomas and leukemias. The segment's leadership is further strengthened by the robust pipeline of cell-based immunotherapy products targeting B-cell malignancies and the demonstrated clinical efficacy of existing treatments. Additionally, the segment is experiencing the highest growth rate in the market, projected to expand at approximately 15% from 2024 to 2029, driven by continuous technological advancements in CAR T-cell therapy development and increasing regulatory approvals for new treatments targeting B-cell malignancies.

Remaining Segments in Primary Indication Market

The cell-based immunotherapy market encompasses several other significant segments, including prostate cancer, renal cell carcinoma, liver cancer, and other primary indications. The prostate cancer segment has emerged as a crucial area for cell-based immunotherapy development, with dendritic cell-based vaccines showing promising results in clinical applications. Renal cell carcinoma treatment has witnessed notable advancements through innovative cell-based approaches, particularly with the development of targeted immunotherapy solutions. The liver cancer segment continues to evolve with new therapeutic strategies, while other primary indications, including various solid tumors, are gaining traction through emerging cell-based treatment modalities. These segments collectively represent diverse opportunities for market growth, supported by ongoing research and development initiatives across multiple cancer types.

Global Cell Based Immunotherapy Market Geography Segment Analysis

Cell-Based Immunotherapy Market in North America

North America represents a dominant force in the global cell-based immunotherapy market, driven by robust healthcare infrastructure, significant research and development activities, and high adoption rates of advanced therapeutic options. The region benefits from the presence of major pharmaceutical companies, research institutions, and a favorable regulatory environment that supports innovation in cellular immunotherapy. The United States, Canada, and Mexico collectively contribute to the region's market leadership, with each country demonstrating unique strengths in terms of research capabilities, healthcare delivery systems, and market access strategies.

Market Analysis of Global Cell Based Immunotherapy Market: Forecasted Growth Rate by Region

Cell-Based Immunotherapy Market in the United States

The United States maintains its position as the largest market for cell-based immunotherapy in North America, commanding approximately 81% of the regional market share. The country's leadership is attributed to its advanced healthcare system, substantial investment in research and development, and the presence of key market players. The robust pipeline of cell-based immunotherapies products, coupled with favorable reimbursement policies and increasing awareness among healthcare providers and patients, continues to drive market growth. The presence of major research institutions and cancer treatment centers, along with significant government funding for immunotherapy research, further strengthens the United States' position in the market.

Cell-Based Immunotherapy Market in the United States - Growth Analysis

The United States is also experiencing the highest growth rate in North America, with a projected CAGR of approximately 16% from 2024 to 2029. This growth is fueled by increasing cancer prevalence, expanding therapeutic applications of cell-based immunotherapies, and continuous technological advancements in the field. The country's commitment to precision medicine initiatives, coupled with rising investment in CAR-T cell therapy development and other innovative approaches, supports this robust growth trajectory. The expansion of manufacturing facilities and increasing clinical trials for novel cell-based immunotherapy further contribute to the market's dynamic growth.

Cell-Based Immunotherapy Market in Europe

Europe represents a significant market for cell-based immunotherapy, characterized by strong research capabilities, advanced healthcare systems, and increasing adoption of innovative therapeutic approaches. The region's market is driven by collaborative research initiatives, substantial healthcare spending, and supportive regulatory frameworks. Germany, the United Kingdom, France, Italy, and Spain are the key contributors to the European market, each bringing unique strengths in terms of research infrastructure, clinical expertise, and market access strategies.

Cell-Based Immunotherapy Market in Germany

Germany emerges as the largest market for cell-based immunotherapy in Europe, holding approximately 26% of the regional market share. The country's leadership position is supported by its robust healthcare infrastructure, significant investment in research and development, and strong presence of biotechnology companies. Germany's commitment to advancing cellular therapies, coupled with its well-established healthcare reimbursement system and growing number of specialized treatment centers, continues to drive market growth.

Cell-Based Immunotherapy Market in France

France demonstrates the highest growth potential in the European market, with a projected CAGR of approximately 16% from 2024 to 2029. The country's impressive growth is driven by increasing investment in cellular therapy research, expanding clinical trial activities, and growing adoption of advanced treatment options. France's strong focus on innovative healthcare solutions, coupled with its well-developed research infrastructure and supportive regulatory environment, positions it as a key growth driver in the European market.

Cell-Based Immunotherapy Market in Asia-Pacific

The Asia-Pacific region represents a rapidly evolving market for cell-based immunotherapy, characterized by increasing healthcare expenditure, growing research capabilities, and rising awareness about advanced therapeutic options. The region encompasses diverse markets including China, Japan, India, Australia, and South Korea, each contributing uniquely to the market's development. The presence of large patient populations, improving healthcare infrastructure, and growing investment in biotechnology research creates significant opportunities for market expansion.

Cell-Based Immunotherapy Market in China

China stands as the largest market for cell-based immunotherapy in the Asia-Pacific region, demonstrating strong growth potential and significant market influence. The country's leadership is driven by substantial investment in healthcare infrastructure, growing research and development activities, and increasing focus on innovative therapeutic approaches. China's large patient population, coupled with government support for biotechnology development and expanding manufacturing capabilities, reinforces its position as a key market in the region.

Cell-Based Immunotherapy Market in India

India emerges as the fastest-growing market in the Asia-Pacific region, showing remarkable potential in the cell-based immunotherapy sector. The country's growth is driven by increasing healthcare expenditure, rising awareness about advanced treatment options, and growing research activities in cellular therapy. India's expanding biotechnology sector, coupled with government initiatives to promote healthcare innovation and improving access to advanced therapies, positions it as a significant growth driver in the regional market.

Cell-Based Immunotherapy Market in the Middle East and Africa

The Middle East and Africa region presents an emerging market for cell-based immunotherapy, characterized by growing healthcare infrastructure and increasing awareness about advanced treatment options. The region's market development is supported by rising healthcare expenditure, particularly in GCC countries, and growing focus on improving cancer care facilities. Within the region, GCC countries emerge as the largest market, while South Africa shows the fastest growth potential, driven by improving healthcare infrastructure and increasing investment in advanced therapeutic options.

Cell-Based Immunotherapy Market in South America

South America demonstrates growing potential in the cell-based immunotherapy market, supported by increasing healthcare expenditure and rising awareness about advanced treatment options. The region's market is characterized by improving research infrastructure, growing clinical trial activities, and rising adoption of innovative therapies. Brazil emerges as both the largest and fastest-growing market in the region, driven by its substantial healthcare system, increasing research activities, and growing focus on advanced therapeutic options. Argentina also contributes significantly to the regional market, with expanding healthcare infrastructure and rising investment in biotechnology research.

Cell-Based Immunotherapy Industry Overview

Top Companies in Cell-Based Immunotherapy Market

The cell-based immunotherapy market is led by established pharmaceutical giants including Novartis AG, Gilead Sciences (Kite Pharma), Bristol-Myers Squibb, Johnson & Johnson, and Pfizer, alongside specialized players like Dendreon Pharmaceuticals and GC Biopharma. These companies are heavily investing in research and development to expand their product portfolios, particularly in CAR T-cell therapy and dendritic cell-based vaccines. Strategic collaborations and licensing agreements have become increasingly common to accelerate product development and market access. Companies are focusing on expanding their manufacturing capabilities through new facilities and technology investments, while simultaneously working on improving production efficiency and reducing costs. The industry has witnessed significant advancements in targeting mechanisms and delivery systems, with companies developing proprietary platforms and technologies to enhance treatment efficacy.

Dynamic Market Structure Drives Industry Evolution

The cell-based immunotherapy market exhibits a relatively concentrated structure dominated by large pharmaceutical conglomerates with extensive R&D capabilities and robust manufacturing infrastructure. These major players leverage their established presence in oncology and immunology to maintain market leadership, while specialized biotech firms focus on developing novel therapeutic approaches and technologies. The market has witnessed significant consolidation through strategic acquisitions, particularly of innovative biotech companies by larger pharmaceutical firms seeking to expand their cell therapy capabilities and product pipelines. This trend is exemplified by transactions such as Gilead's acquisition of Kite Pharma and Bristol-Myers Squibb's acquisition of Celgene, which included valuable cell therapy assets.


The competitive landscape is characterized by a mix of global and regional players, with different companies focusing on specific therapeutic areas or technologies within the cell-based immunotherapies manufacturers space. Market entry barriers are substantial due to high development costs, complex manufacturing requirements, and stringent regulatory standards. Companies are increasingly establishing regional manufacturing facilities to better serve local markets and ensure supply chain reliability. The industry has also seen the emergence of strategic partnerships between pharmaceutical companies and academic institutions or research organizations to accelerate innovation and clinical development.

Innovation and Scale Drive Market Success

Success in the immune cell therapy drugs market increasingly depends on companies' ability to innovate while achieving operational scale and efficiency. Incumbent players must continue investing in next-generation technologies and manufacturing processes while expanding their therapeutic indications and geographical presence. Building robust clinical evidence through successful trials and real-world data is crucial for maintaining market position. Companies need to develop strategies for reducing manufacturing costs and improving accessibility while maintaining product quality and efficacy. Additionally, establishing strong relationships with healthcare providers and developing comprehensive patient support programs are becoming increasingly important for market success.


For emerging players and contenders, differentiation through novel therapeutic approaches or improved delivery systems presents opportunities for market entry and growth. Success factors include developing proprietary technology platforms, establishing strategic partnerships for manufacturing and commercialization, and focusing on underserved therapeutic areas or patient populations. Companies must navigate complex regulatory requirements while building evidence for clinical efficacy and safety. The ability to secure adequate funding for development and commercialization, along with establishing efficient production processes, remains crucial. Future success will also depend on addressing challenges related to patient access, reimbursement, and healthcare system integration.

Cell-Based Immunotherapy Market Leaders

  1. Novartis AG

  2. Gilead Sciences, Inc (Kite Pharma)

  3. Dendreon Pharmaceuticals LLC

  4. JW CreaGene Co., Ltd

  5. GC Biopharma Corporation

  6. *Disclaimer: Major Players sorted in no particular order
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Cell-Based Immunotherapy Market News

  • In October 2022, Allogene Therapeutics, Inc., a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T) products for cancer, launched CAR T Together, a first-of-its-kind effort comprised of clinical trial investigators who represent the field of clinicians committed to supporting the development of 'off-the-shelf' (allogeneic) chimeric antigen receptor (CAR) T products to make CAR T therapy scalable and more accessible to patients with certain cancers.
  • In April 2022, Gilead Company's Yescarta received FDA approval as the first CAR T-cell therapy for the initial treatment of relapsed or refractory large B-cell lymphoma (LBCL).

Cell-Based Immunotherapy Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Rising Prevalence of Cancer
    • 4.2.2 Technological Advancement in Developing Target Based Anti-Cancer Therapies
    • 4.2.3 Launches and Approval of Different Cell-based Immunotherapy Drugs
  • 4.3 Market Restraints
    • 4.3.1 High Cost of Technology
    • 4.3.2 Lack of Awareness in the Developing Markets
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Therapy
    • 5.1.1 Autologous Cellular Immunotherapy
    • 5.1.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy
    • 5.1.3 Dendritic Cell-based Vaccine Therapy
  • 5.2 By Primary Indication
    • 5.2.1 B-cell Malignancies
    • 5.2.2 Prostate Cancer
    • 5.2.3 Renal Cell Carcinoma
    • 5.2.4 Liver Cancer
    • 5.2.5 Other Primary Indications
  • 5.3 Geography
    • 5.3.1 North America
    • 5.3.1.1 United States
    • 5.3.1.2 Canada
    • 5.3.1.3 Mexico
    • 5.3.2 Europe
    • 5.3.2.1 Germany
    • 5.3.2.2 United Kingdom
    • 5.3.2.3 France
    • 5.3.2.4 Italy
    • 5.3.2.5 Spain
    • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
    • 5.3.3.1 China
    • 5.3.3.2 Japan
    • 5.3.3.3 India
    • 5.3.3.4 Australia
    • 5.3.3.5 South Korea
    • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle East and Africa
    • 5.3.4.1 GCC
    • 5.3.4.2 South Africa
    • 5.3.4.3 Rest of Middle East and Africa
    • 5.3.5 South America
    • 5.3.5.1 Brazil
    • 5.3.5.2 Argentina
    • 5.3.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Novartis AG
    • 6.1.2 Gilead Sciences, Inc (Kite Pharma)
    • 6.1.3 GC Biopharma Corporation
    • 6.1.4 Dendreon Pharmaceuticals LLC
    • 6.1.5 JW CreaGene Co., Ltd
    • 6.1.6 GC Biopharma Corporation
    • 6.1.7 Johnson and Johnson (Janssen Global Services, LLC)
    • 6.1.8 Pfizer Inc.
    • 6.1.9 F. Hoffmann-La Roche Ltd
    • 6.1.10 GlaxoSmithKline plc
    • 6.1.11 Celyad
    • 6.1.12 Bristol-Myers Squibb Company
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments
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Cell-Based Immunotherapy Industry Segmentation

As per the scope of the report, cell-based immunotherapy uses a cell type from the immune system as a therapeutic agent. The cells are first removed from the body, then activated or modified, expanded, and finally re-infused into the patient in this procedure. Cell-based immunotherapy is also known as adoptive cell therapy and is used to treat cancer. 

The cell-based immunotherapy market is segmented by Therapy (Autologous Cellular Immunotherapy, Chimeric Antigen Receptor (CAR) T-Cell Therapy, Dendritic Cell-based Vaccine Therapy), Primary Indication (B-cell Malignancies, Prostate Cancer, Renal Cell Carcinoma, Liver Cancer, and others) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Therapy Autologous Cellular Immunotherapy
Chimeric Antigen Receptor (CAR) T-Cell Therapy
Dendritic Cell-based Vaccine Therapy
By Primary Indication B-cell Malignancies
Prostate Cancer
Renal Cell Carcinoma
Liver Cancer
Other Primary Indications
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
South America Brazil
Argentina
Rest of South America
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Cell-Based Immunotherapy Market Research FAQs

How big is the Global Cell Based Immunotherapy Market?

The Global Cell Based Immunotherapy Market size is expected to reach USD 5.24 billion in 2025 and grow at a CAGR of 14.98% to reach USD 10.54 billion by 2030.

What is the current Global Cell Based Immunotherapy Market size?

In 2025, the Global Cell Based Immunotherapy Market size is expected to reach USD 5.24 billion.

Who are the key players in Global Cell Based Immunotherapy Market?

Novartis AG, Gilead Sciences, Inc (Kite Pharma), Dendreon Pharmaceuticals LLC, JW CreaGene Co., Ltd and GC Biopharma Corporation are the major companies operating in the Global Cell Based Immunotherapy Market.

Which is the fastest growing region in Global Cell Based Immunotherapy Market?

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Global Cell Based Immunotherapy Market?

In 2025, the North America accounts for the largest market share in Global Cell Based Immunotherapy Market.

What years does this Global Cell Based Immunotherapy Market cover, and what was the market size in 2024?

In 2024, the Global Cell Based Immunotherapy Market size was estimated at USD 4.46 billion. The report covers the Global Cell Based Immunotherapy Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Cell Based Immunotherapy Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Global Cell Based Immunotherapy Market Research

Mordor Intelligence provides a comprehensive analysis of the cell-based immunotherapy market, drawing on extensive experience in healthcare industry research. Our expert analysts offer detailed insights into various segments. These include cellular immunotherapy technologies, CAR T cellular immunotherapy developments, and dendritic cell cancer vaccine immunotherapy innovations. The report extensively covers immune cell therapy drugs market dynamics and emerging immune cell storage service offerings. This provides stakeholders with crucial data for informed decision-making.

The report is available as an easy-to-download PDF and offers valuable insights into immunotherapy cost structures and industry trends. It examines the role of leading cell-based immunotherapies manufacturers in shaping market dynamics. Stakeholders gain access to detailed analysis of adoptive cellular immunotherapy advancements and emerging treatment modalities. Our comprehensive coverage helps healthcare providers, investors, and manufacturers understand market dynamics, technological innovations, and regulatory frameworks affecting the cell-based immunotherapies landscape. This enables strategic planning and competitive positioning.