Bone Grafts And Substitutes Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 3.95 Billion |
| Market Size (2029) | USD 5.70 Billion |
| CAGR (2024 - 2029) | 5.70 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Bone Grafts And Substitutes Market Analysis
The Bone Grafts And Substitutes Market size is estimated at USD 3.95 billion in 2024, and is expected to reach USD 5.70 billion by 2029, growing at a CAGR of 5.70% during the forecast period (2024-2029).
The major factors driving the growth of the bone grafts and substitutes market include the rising number of road injuries and joint disorders, the development of biocompatible synthetic bone grafts, and the increase in demand for dental bone grafts.
The rising incidence of road injuries and the prevalence of joint disorders are the key factors driving the demand for bone grafting. According to the French Road Safety Observatory report published in February 2024, 1,101 individuals were reported with serious injuries in January 2024 in France, mirroring the figures from January 2023. Thus, the growing burden of road accidents and the subsequent increase in bone-related injuries is expected to drive the market growth.
Furthermore, the rising company activities in launching advanced products are expected to increase the demand for bone grafts and substitutes, thereby boosting market growth. For instance, in August 2023, Stimlabs LLC unveiled Relese, an allograft made from a fenestrated dehydrated complete human placental membrane (dCHPM), targeting both chronic and acute wounds. Relese acts as a selective barrier, featuring channels that facilitate wound fluid drainage while safeguarding the wound from external elements. This thicker, specialized allograft boasts superior handling properties, rendering it suitable for a wide array of clinical applications.
Additionally, the increase in regulatory approvals for various bone graft products is expected to boost the market growth over the forecast period. For instance, in October 2023, Orthofix Medical Inc., a leading global spine and orthopedics company, received the 510k clearance and a full commercial launch of OsteoCove, an advanced bioactive synthetic graft. Available in both a putty and strip configuration, OsteoCove was carefully formulated to provide superior bone-forming capabilities with best-in-class handling characteristics for a wide range of spine and orthopedic procedural applications. Thus, owing to the strategic product launches of bone grafts and significant regulatory clearances, the market studied is expected to grow significantly over the forecast period.
Thus, owing to the increase in the incidence of bone-related diseases and product launches by key players, the market studied is expected to witness significant growth over the coming years. However, factors such as the high cost of surgeries and ethical issues related to bone grafting are likely to restrain the market growth over the forecast period.
Bone Grafts And Substitutes Industry Segmentation
The Dental Segment is Expected to Register Significant Growth in the Market Studied Over the Forecast Period
The dental segment is expected to witness significant growth in the market owing to factors such as the rising incidence of dental diseases among the population and increasing dental visits. Also, advancements in dental graft systems coupled with a rise in strategic activities may augment the market growth over the forecast period.
The increasing burden of dental diseases such as dental caries and periodontal diseases among the population is likely to boost the demand for dental surgeries and increase the number of dental visits. For instance, according to the 2022-2023 Annual Report of the NHS Dental Statistics for England, 32.5 million dental courses of treatment were delivered from 2022 to 2023 in the country, an increase of 23.2% compared to the previous year. Thus, an increase in dental procedures and visits may increase the chances of adopting dental grafts and substitutes for different dental diseases, thereby promoting market growth over the forecast period.
Furthermore, the rising adoption of various business strategies such as acquisition, collaboration, and product launches by the companies is also contributing to the growth of the market. For instance, in April 2023, ZimVie Inc. unveiled two new additions to its biomaterials portfolio. The first, the RegenerOss CC Allograft Particulate, is a natural blend of cortical and cancellous bone particles designed to fill bony voids in various dental applications. The second, the RegenerOss Bone Graft Plug, offers a user-friendly solution for filling extraction sockets and addressing periodontal defects. Both products are accessible throughout North America. Hence, owing to such advanced product launches, the dental segment is expected to witness notable growth over the forecast period.
Thus, due to the increase in dental diseases and the rise in strategic activities by the key players, the dental segment is expected to witness significant growth over the forecast period.
North America is Expected to Record Significant Market Share Over the Forecast Period
North America is expected to record significant market growth in the bone grafts and substitutes market over the forecast period owing to factors such as the increasing prevalence of joint disorders and dental diseases, growing dental visits, rising technological advancement, and the presence of a well-established healthcare infrastructure.
The burden of dental diseases and joint-related disorders such as osteoarthritis, arthritis, and rheumatoid arthritis among the population is increasing rapidly, which is likely to increase the demand for bone grafting procedures for removing small bones from grinding against each other to provide relief and remove the inflamed bone from the area, thereby propelling the market growth.
For instance, according to Statistics Canada’s November 2023 update, 6.2 million adult Canadians aged 65 years and over were diagnosed with arthritis in 2022. The prevalence of arthritis increases with age and is higher among females. Similarly, according to the February 2024 update by CIHI, the second most common inpatient surgery in Canada in 2022–2023 was knee replacement (2.6 days) and hip replacement (6.1 days). Consequently, rising bone-related ailments, extended hospital stays, and associated diseases are projected to drive growth in the bone grafts and substitutes market during the forecast period.
Moreover, the rising focus on research and development activities by companies, regulatory approvals, adoption of bone grafts by patients, and increasing product launches are also contributing to the market's growth.
For instance, in May 2024, OssDsign AB (publ.) reported that 5,000 patients benefited from the cutting-edge nanosynthetic bone graft OssDsign Catalyst. In September 2023, graft was used to treat 2,000 patients, up from 1,000 in May 2023. OssDsign Catalyst, a nanosynthetic bone graft, promotes the development of healthy bone tissue during spinal fusion surgeries. This graft features a unique nanocrystalline structure, which the body gradually resorbs, subsequently replacing it with new, healthy bone tissues. Thus, the abovementioned strategic activities by the key players in North America are expected to augment the market growth.
Thus, considering the rising incidence of dental diseases and joint disorders and increasing product launches in the region, the bone grafts and substitutes market is expected to grow rapidly over the forecast period.
Bone Grafts And Substitutes Industry Overview
The bone grafts and substitutes market is competitive, with the presence of several local and international companies. The rising technological developments in the field of bone grafts and substitutes are expected to support the growth of the market studied across the world. Some of the key players in the market are Medtronic PLC, Stryker Corporation, Smith+Nephew, and SeaSpine.
Bone Grafts And Substitutes Market Leaders
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Medtronic Plc
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Zimmer Biomet
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Stryker Corporation
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Johnson and Johnson
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Smith+Nephew
*Disclaimer: Major Players sorted in no particular order
Bone Grafts And Substitutes Market News
- July 2024: BS Dental, one of the leaders in cutting-edge dental instruments and solutions, launched its newest product line, REGEN. This line features advanced bone and membrane materials, raising the bar for regenerative procedures.
- June 2024: Biogennix, a company at the forefront of osteobiologics and bone graft procedures, unveiled a comprehensive scientific study detailing the advanced properties of its TrelCor bone graft material. TrelCor, an innovative dual-phase bone graft, boasts a nanocrystalline hydroxycarbanoapatite (HCA) surface that is meticulously designed to enhance bone formation.
Bone Grafts And Substitutes Market Report - Table of Contents
1. INTRODUCTION
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Rising Incidence of Road Injuries and Joint Disorders
4.2.2 Development of Biocompatible Synthetic Bone Grafts
4.2.3 Increase in the Demand for Dental Bone Grafts
4.3 Market Restraints
4.3.1 High Cost of Surgeries
4.3.2 Ethical Issues Related to Bone Grafting
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION (Market Size by Value in USD)
5.1 By Product
5.1.1 Allografts
5.1.2 Bone Graft Substitutes
5.1.3 Other Products
5.2 By Application
5.2.1 Craniomaxillofacial
5.2.2 Dental
5.2.3 Joint Reconstruction
5.2.4 Spinal Fusion
5.2.5 Other Applications
5.3 Geography
5.3.1 North America
5.3.1.1 United States
5.3.1.2 Canada
5.3.1.3 Mexico
5.3.2 Europe
5.3.2.1 Germany
5.3.2.2 United Kingdom
5.3.2.3 France
5.3.2.4 Italy
5.3.2.5 Spain
5.3.2.6 Rest of Europe
5.3.3 Asia-Pacific
5.3.3.1 China
5.3.3.2 Japan
5.3.3.3 India
5.3.3.4 Australia
5.3.3.5 South Korea
5.3.3.6 Rest of Asia-Pacific
5.3.4 Middle East and Africa
5.3.4.1 GCC
5.3.4.2 South Africa
5.3.4.3 Rest of Middle East and Africa
5.3.5 South America
5.3.5.1 Brazil
5.3.5.2 Argentina
5.3.5.3 Rest of South America
6. COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.1 Zimmer Biomet
6.1.2 Stryker Corporation
6.1.3 Smith+Nephew
6.1.4 Medtronic PLC
6.1.5 Johnson and Johnson
6.1.6 Baxter International Inc
6.1.7 Graftys
6.1.8 Orthofix Holdings Inc.
6.1.9 Geistlich Pharma AG
6.1.10 SeaSpine
6.1.11 PuraGraft.com
6.1.12 XeliteMed
- *List Not Exhaustive
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
Bone Grafts And Substitutes Industry Segmentation
As per the scope of the report, bone graft is a surgical procedure in which diseased or damaged bones are repaired and rebuilt using transplanted bones. These are implantable materials that promote bone healing, bone formation, and osseous reconstruction due to their osteoconductive, osteogenic, and osteoinductive properties. Bone grafts can also be used to fill voids in case of the absence of bones or to provide structural stability.
The bone grafts and substitutes market is segmented by product, application, and geography. By product, the market is segmented into allografts, bone graft substitutes, and other products. By application, the market is segmented into craniomaxillofacial, dental, joint reconstruction, spinal fusion, and other applications. By geography, the market is segmented into North America, Europe, Asia-Pacific, Middle East and Africa, and South America. The market report also covers the estimated market sizes and trends for 17 countries across major regions globally. For each segment, the market size and forecast are provided in terms of value (USD).
| By Product | |
| Allografts | |
| Bone Graft Substitutes | |
| Other Products |
| By Application | |
| Craniomaxillofacial | |
| Dental | |
| Joint Reconstruction | |
| Spinal Fusion | |
| Other Applications |
| Geography | ||||||||
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Bone Grafts And Substitutes Market Research Faqs
How big is the Bone Grafts And Substitutes Market?
The Bone Grafts And Substitutes Market size is expected to reach USD 3.95 billion in 2024 and grow at a CAGR of 5.70% to reach USD 5.70 billion by 2029.
What is the current Bone Grafts And Substitutes Market size?
In 2024, the Bone Grafts And Substitutes Market size is expected to reach USD 3.95 billion.
Who are the key players in Bone Grafts And Substitutes Market?
Medtronic Plc, Zimmer Biomet, Stryker Corporation, Johnson and Johnson and Smith+Nephew are the major companies operating in the Bone Grafts And Substitutes Market.
Which is the fastest growing region in Bone Grafts And Substitutes Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in Bone Grafts And Substitutes Market?
In 2024, the North America accounts for the largest market share in Bone Grafts And Substitutes Market.
What years does this Bone Grafts And Substitutes Market cover, and what was the market size in 2023?
In 2023, the Bone Grafts And Substitutes Market size was estimated at USD 3.72 billion. The report covers the Bone Grafts And Substitutes Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Bone Grafts And Substitutes Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
Bone Grafts And Substitutes Industry Report
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Bone Grafts And Substitutes Market Report Snapshots
