Antihistamine Market Size & Share Analysis - Growth Trends & Forecast (2025 - 2030)

The Antihistamine Market Report is Segmented by Drug Class (H1 Antihistamines [First Generation and Second Generation], H2 Antihistamines, and H3 Antihistamines), Dosage Form (Oral Route, Parenteral Route, and Other Dosage Forms), Type (OTC and Prescription-Based), Disease (Allergic Disorders, Stomach Disorders, Central Nervous System Disorders, and Other Diseases), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Report Offers the Market Size in Value (USD) for all the Abovementioned Segments.

Antihistamine Market Size & Share Analysis - Growth Trends & Forecast (2025 - 2030)

Antihistamine Market Size

Antihistamine Market Summary
Study Period 2019 - 2030
Base Year For Estimation 2024
Forecast Data Period 2025 - 2030
CAGR 7.70 %
Fastest Growing Market Asia Pacific
Largest Market North America
Market Concentration Low

Major Players

Antihistamine Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Antihistamine Market Analysis

The Antihistamine Market is expected to register a CAGR of 7.7% during the forecast period.

The market’s growth is driven by factors like rising allergies and stomach disorders issues and increasing research and development activities for novel dosage forms. The rising burden of allergies and acid reflex are anticipated to drive the market's growth during the forecast period. For instance, according to the data published by the Asthma and Allergy Foundation of America in April 2024, nearly one-third of American adults and over a quarter of American children suffer from seasonal allergies, eczema, or food allergies each year.

According to a study published in Rawal Medical Journal in September 2022, the prevalence of gastroesophageal reflux disease (GERD) was found to be 18.1% to 27.8% in North America, 8.8% to 25.9% in Europe, 2.5% to 7.8% in East Asia, 8.7% to 33.1% in the Middle East, 11.6% in Australia, and 23% in South America. Therefore, such a massive prevalence of allergies and stomach disorders is anticipated to increase the demand for antihistamines, driving market growth.

Furthermore, companies’ strategic activities, such as collaborations and agreements in using antihistamine medications, are anticipated to bolster market growth during the forecast period. For instance, in March 2023, Astepro Allergy partnered with Meghann Fahy to help patients suffering from allergies. Astepro is a long-lasting nasal spray that starts working in 30 minutes and can relieve allergy symptoms quickly. Therefore, such partnerships increase the usage of antihistamines, which is anticipated to increase their adoption among people and drive market growth.

Therefore, the rising issues of allergies and stomach disorders and the company's strategic activities are anticipated to drive market growth. However, the patent expiry of branded drugs, the introduction of generic drugs, and the adverse effects associated with antihistamine drugs are impeding market growth.

Antihistamine Industry Overview

The antihistamine market is fragmented, with several players holding a global market share. Factors owing to the competition include rising initiatives from the market players, such as launches and partnerships, and rising approvals of antihistamines, among others. Some of the players operating in the market include Johnson and Johnson, Novartis AG, Pfizer Inc., Merck and Co., Bayer AG, GSK, Almirall, and Akorn.

Antihistamine Market Leaders

  1. Johnson and Johnson

  2. Novartis

  3. Pfizer

  4. Merck and Co.

  5. Bayer

  6. *Disclaimer: Major Players sorted in no particular order
Antihistamine Market Concentration
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Antihistamine Market News

  • January 2024: Dr. Reddy’s Laboratories (UK) Ltd launched its new allergy medication, Histallay (fexofenadine hydrochloride), in the UK general sales list (GSL) market.
  • April 2023: Ocumension Therapeutics, an exclusive Chinese partner of Nicox SA, submitted a new drug application (NDA) for approval to commercialize Zerviate (cetirizine ophthalmic solution) 0.24% in China for ocular itching associated with allergic conjunctivitis. The product is expected to be launched in China in 2024.

Antihistamine Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumption and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Rising Issues of Allergies and Stomach Disorders
    • 4.2.2 Increase in R&D Activities Leading to Development of Novel Dosage Forms
    • 4.2.3
  • 4.3 Market Restraints
    • 4.3.1 Patent Expiry and Introduction of Generic Drugs
    • 4.3.2 Adverse Effects Associated with Antihistamine Drugs
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD)

  • 5.1 By Drug Class
    • 5.1.1 H1 Antihistamanics
    • 5.1.1.1 First Generation
    • 5.1.1.2 Second Generation
    • 5.1.2 H2 Anti histamanics
    • 5.1.3 H3 Anti histamanics
  • 5.2 By Dosage Form
    • 5.2.1 Oral route
    • 5.2.2 Parenteral
    • 5.2.3 Other Dosage Forms
  • 5.3 By Type
    • 5.3.1 OTC
    • 5.3.2 Prescription-based
  • 5.4 By Disease
    • 5.4.1 Allergic Disorders
    • 5.4.2 Stomach Disorders
    • 5.4.3 Central Nervous System Disorders
    • 5.4.4 Other Diseases
  • 5.5 By Distribution Channels
    • 5.5.1 Hospital Pharmacies
    • 5.5.2 Retail Pharmacies
    • 5.5.3 Online Pharmacies
  • 5.6 By Geography
    • 5.6.1 North America
    • 5.6.1.1 United States
    • 5.6.1.2 Canada
    • 5.6.1.3 Mexico
    • 5.6.2 Europe
    • 5.6.2.1 Germany
    • 5.6.2.2 United Kingdom
    • 5.6.2.3 France
    • 5.6.2.4 Italy
    • 5.6.2.5 Spain
    • 5.6.2.6 Rest of Europe
    • 5.6.3 Asia-Pacific
    • 5.6.3.1 China
    • 5.6.3.2 Japan
    • 5.6.3.3 India
    • 5.6.3.4 Australia
    • 5.6.3.5 South Korea
    • 5.6.3.6 Rest of Asia-Pacific
    • 5.6.4 Middle East and Africa
    • 5.6.4.1 GCC
    • 5.6.4.2 South Africa
    • 5.6.4.3 Rest of Middle East and Africa
    • 5.6.5 South America
    • 5.6.5.1 Brazil
    • 5.6.5.2 Argentina
    • 5.6.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Bayer
    • 6.1.2 Almirall
    • 6.1.3 GSK PLC
    • 6.1.4 AstraZeneca
    • 6.1.5 Johnson and Johnson
    • 6.1.6 Novartis
    • 6.1.7 Sanofi
    • 6.1.8 Pfizer
    • 6.1.9 Sun Pharmaceutical Industries Limited
    • 6.1.10 Akorn
    • 6.1.11 Merck and Co.
    • 6.1.12 Teva Pharmaceutical
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Antihistamine Industry Segmentation

As per the report's scope, antihistamines, a common medication class, are primarily employed to alleviate allergy symptoms. They combat conditions triggered by the body's overproduction of histamine, an immune system byproduct. Predominantly, antihistamines cater to individuals grappling with allergic responses to pollen and other allergens. Beyond allergies, they find utility in managing a spectrum of conditions, spanning from anxiety and colds to gastrointestinal maladies.

The antihistamine market is segmented by drug class, dosage form, type, disease, distribution channels, and geography. By drug class, the market is segmented into H1 antihistamines, H2 antihistamines, and H3 antihistamines. The H1 antihistamines segment is sub-segmented into first-generation and second-generation. By dosage form, the market is segmented into oral route, parenteral route, and other dosage forms. By type, the market is segmented into OTC and prescription-based. By disease, the market is segmented into allergic disorders, stomach disorders, central nervous system disorders, and other diseases. By distribution channels, the market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. By geography, the market is segmented into North America, Europe, Asia-Pacific, Middle East and Africa, and South America. The market report also covers the estimated market sizes and trends for 17 countries across major global regions. The report offers the value (USD) for the above segments.

By Drug Class H1 Antihistamanics First Generation
Second Generation
H2 Anti histamanics
H3 Anti histamanics
By Dosage Form Oral route
Parenteral
Other Dosage Forms
By Type OTC
Prescription-based
By Disease Allergic Disorders
Stomach Disorders
Central Nervous System Disorders
Other Diseases
By Distribution Channels Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
By Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
South America Brazil
Argentina
Rest of South America
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Antihistamine Market Research FAQs

What is the current Antihistamine Market size?

The Antihistamine Market is projected to register a CAGR of 7.70% during the forecast period (2025-2030)

Who are the key players in Antihistamine Market?

Johnson and Johnson, Novartis, Pfizer, Merck and Co. and Bayer are the major companies operating in the Antihistamine Market.

Which is the fastest growing region in Antihistamine Market?

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Antihistamine Market?

In 2025, the North America accounts for the largest market share in Antihistamine Market.

What years does this Antihistamine Market cover?

The report covers the Antihistamine Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Antihistamine Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Antihistamine Industry Report

Statistics for the 2025 Antihistamine market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Antihistamine analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.