Market Trends of Anticoagulant Reversal Drugs Industry
This section covers the major market trends shaping the Anticoagulant Reversal Drugs Market according to our research experts:
The Coagulation Factors Segment is Expected to Hold the Largest Market Share
Coagulation factors, also called clotting factors, are the proteins in the blood. They help form a blood clot to stop bleeding when an injury occurs.
It has been observed that COVID-19 caused blood clotting in most patients, propelling the demand for anticoagulants during the pandemic. According to a research article published in the Lancet in 2020, coagulopathy of varying severity was observed in most COVID-19-infected patients, characterized by increased D-dimer levels and fibrinogen or fibrin degradation products, along with abnormal measurements in the prothrombin time, acute partial thromboplastin time, and platelet counts. Hence, thorough research on various factors affecting bleeding and coagulation among COVID-19 patients was carried out to understand the pathophysiology of the causal organism.
Besides, Andexxa is the first and only approved drug for reversing the effect of coagulation factor Xa inhibitors in adult patients. Portola Pharmaceuticals introduced Andexxa in the year 2018, which contributed to a major share of the company's revenue. Currently, Andexxa is sold by AstraZeneca because it acquired Alexion Pharmaceuticals, the parent company of Portola Pharmaceuticals in July 2021.
Additionally, the increasing research activities in the development of new products by companies are expected to drive the growth of the studied segment over the forecast period. For instance, the American College of Cardiology stated in its June 2022 study that for atrial fibrillation, there will be a growing new drug development wave that will fulfill the need for anticoagulants in the coming years. With the focus of companies on developing anticoagulants, the segment is believed to witness strong growth over the forecast period.
North America Dominates the Market and is Expected to do the Same in the Forecast Period
North America is expected to dominate the overall anticoagulant reversal drugs market throughout the forecast period. The high growth of the studied market in North America is due to factors such as the availability of direct reimbursement policies and the region's advanced healthcare infrastructure.
COVID-19 significantly impacted the market studied in the North American region due to the emergence of the relationship between COVID-19 infection and blood disorders. For instance, as per 2020 data from the American Journal of Hematology, COVID-19-infected patients admitted with severe complications associated with the viral infection were found to exhibit high levels of blood-clotting protein Factor V, which could eventually lead to the development of blood clots in various organs.
Moreover, the United States holds the largest market share due to the accelerated drug approval initiative by the US FDA and the initiation of various prevention programs and awareness workshops for blood disorders by the CDC, which is expected to drive market growth in this region. Also, the high prevalence of cardiovascular diseases in the United States drives the studied market. According to the American Heart Association 2021 data, myocardial infarction is more common in the United States and it has been observed that every 40 seconds at least one person have a myocardial infarction. Additionally, coronary events occur in about 1,055,000 individuals annually, including 720,000 new and 335,000 recurrent coronary events.
Additionally, several key players in the studied market have a base in the United States and are expected to explore the market through R&D activities and product approvals. Thus, given the aforementioned factors, the anticoagulant reversal drugs market is anticipated to grow significantly over the forecast period in North America.
