Market Trends of Antibody Contract Development And Manufacturing Organization Industry
Monoclonal Antibodies Segment is Expected to Hold Significant Market Share Over the Forecast Period
- Due to several critical factors, the monoclonal antibody segment is the fastest-growing segment in the antibody CDMO market. Monoclonal antibodies (mAbs) have demonstrated significant therapeutic potential across various diseases, including cancer, autoimmune disorders, and infectious diseases.
- In addition, several monoclonal antibody therapies have achieved notable success in clinical trials and have received regulatory approvals for various indications. Hence, the biopharmaceutical company is investing in developing monoclonal antibodies, which is anticipated to boost the growth of the antibody CDMO market. For instance, in January 2023, the UK government launched England’s second Investment Zone in Liverpool, in which US pharmaceutical manufacturer TriRx made an initial GBP 10 million (USD 12.22) investment to enhance its capabilities to manufacture monoclonal antibodies.
- Similarly, in September 2023, AbolerIS Pharma announced a EUR 27.3 million (USD 28.83 million) Series A financing for advancing monoclonal antibodies for treating autoimmune diseases such as rheumatoid arthritis. Hence, high investment in monoclonal antibodies is expected to propel the demand for CDMO services, thereby boosting the segment’s growth.
- Biopharmaceutical companies are highly interested in mAb development and manufacturing, as it offers immense potential for growth and profitability. For instance, in October 2022, Fujifilm Diosynth Biotechnologies, a CDMO, partnered with Argenx to manufacture a monoclonal antibody (mAb) fragment called efgartigimod. This mAb will be used to treat patients suffering from severe autoimmune diseases. Monoclonal antibodies have shown remarkable success in treating chronic illnesses by specifically targeting disease-causing molecules or cells, which leads to better patient outcomes. Similarly, in June 2023, Chime Biologics, a CDMO, announced that it had established three-way strategic cooperation with Leads Biolabs and BeiGene to accelerate LBL-007 mAb development and manufacturing for speedy clinical advancement.
- Hence, increasing investment in monoclonal antibodies and strategic collaboration of CDMO with biopharmaceutical companies is anticipated to boost the segment’s growth during the forecast period.
Understand The Key Trends Shaping This Market
Download PDF
North America is Expected to Hold a Significant Market Share Over the Forecast Period
- North America is expected to hold a significant share of the global antibody CDMO market owing to the presence of several established biopharmaceutical companies, increasing research and development activities for antibody therapeutics, rising prevalence of chronic diseases, high investment for antibody therapeutics, and strategic activities by the market players.
- Pharmaceutical companies are investing heavily in R&D, particularly in biologics. This heightened R&D activity increases the need for specialized CDMO services, particularly in antibody development. For instance, in September 2023, Star Therapeutics raised USD 90 million in an oversubscribed Series C financing round to bolster plans for its portfolio companies and antibody therapies. The Series C financing will support the clinical development of VGA039, which is currently in a Phase I trial (NCT05776069). Thus, due to high investment, biotech companies increasingly outsource their development and manufacturing activities to specialized CDMOs to leverage their expertise, reduce costs, and accelerate timelines.
- Moreover, the growing burden of cancer and autoimmune diseases such as rheumatoid arthritis is expected to increase R&D activities and thus propel the demand for CDMO services, likely boosting market growth. For instance, according to the data published by the American Cancer Society (ACS) in January 2024, the incidence of cancer cases will increase from 1.93 million in 2022 to 2.00 million in 2024, an increase of more than 60,000 cases in two years. As per the statistics released in June 2023 by the Centers for Disease Control and Prevention, it is estimated that 25.9% or 78.4 million adults in the United States aged 18 and above will be diagnosed with arthritis by a medical doctor by 2040. This trend is propelling the growth of the monoclonal antibody segment, as CDMOs play a crucial role in customizing and producing these specialized therapies.
- Several companies are penetrating the antibody contract development and manufacturing organization space via acquisition and partnerships. For instance, in October 2023, Eurofins CDMO Alphora Inc. launched a Biologics initiative, focusing on mAbs and therapeutic proteins as part of its vision to diversify and grow within North America's contract development and manufacturing industry.
- Hence, increasing investment in monoclonal antibodies, the growing burden of chronic diseases, and strategic activities by market players are expected to boost the market in North America during the forecast period.
Get Analysis on Important Geographic Markets
Download PDF
