Amniotic Membrane Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 2.99 Billion |
| Market Size (2029) | USD 4.26 Billion |
| CAGR (2024 - 2029) | 12.10 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Amniotic Membrane Market Analysis
The Amniotic Membrane Market size is estimated at USD 2.99 billion in 2024, and is expected to reach USD 4.26 billion by 2029, growing at a CAGR of 12.10% during the forecast period (2024-2029).
- Factors such as a rise in accident and trauma cases, increasing awareness about the benefits of an amniotic membrane, and rising research on stem cell biology and regenerative medicines are the major driving factors for market growth. Additionally, the growing number of surgeries performed and rising expenditure on research and development (R&D) in stem cells and regenerative medicine are key factors driving the overall market.
- For instance, as per the data published by the United States Department of Labor in December 2022, over 5,190 fatal work injuries were reported in the United States in 2022, which increased from 4,764 cases compared to the previous year. Burn injuries represent a significant disease burden on the world population, with nearly 9 million injuries and an estimated 120,000-180,000 deaths annually, as mentioned in the research paper published in October 2022. According to the above-mentioned research, almost 18 million disability-adjusted life years (DALYs) can be accounted for burns, with a disproportionate 90% of this burden borne by LMICs.
- Also, in Bangladesh, Colombia, Egypt, and Pakistan, burn injuries account for up to 18% of permanent disabilities, as per the same research above. The amniotic membrane is commonly used to treat up to second-degree burn wounds. Thus, the rising burden of burn injuries globally is expected to create a high demand for the amniotic membrane for the purpose of tissue repair and regeneration, and it is expected to boost market growth during the forecast period.
- The market consists of several major players, and their strategic product innovation is garnering market growth. For instance, in February 2022, Amnio Technology, a global leader in the development of and distribution of amniotic tissue allografts, launched two new palingen membrane products, palingen dual-layer membrane and dual-layer palingen x-membrane. Like the entire family of PalinGen membrane products, the new allografts are minimally manipulated, homologous, and chorion-free. The palinGen membrane and dual-layer palinGen X-membrane are indicated for patients suffering from non-healing acute and chronic wounds and complex or open surgical wounds and burns. Thus, continuous innovation in the amniotic membrane market is expected to drive the market's overall growth.
- In January 2022, Laboratoires Thea SAS, a prominent independent pharmaceutical company in Europe, finalized the acquisition of seven branded ophthalmic products from Akorn Operating Company LLC. This includes AcellFX, which is an acellular amniotic membrane that offers a protective covering for repairing the ocular surface.
- Therefore, owing to the factors above, it is anticipated that the market will witness growth during the forecast period. However, the lack of standardized guidelines and skilled professionals will likely impede market growth.
Amniotic Membrane Market Trends
The Surgical Wounds Segment is Expected to Grow Significantly During the Forecast Period
- Amniotic membrane has several antimicrobial and biological properties in corneal surgery, as it enhances epithelialization, reinforces adhesion of basal epithelial cells, maintains epithelial phenotype, and modulates the proliferation of normal corneal, conjunctival, and limbal fibroblast. These membranes also prevent apoptosis and inhibit scarring, inflammation, and neovascularization. Several research studies have underlined the diverse applications of amniotic membranes for the surgical treatment of various wounds. For instance, a study published in Membrane in June 2022 highlighted the vast potential of the human amniotic membrane in tissue engineering and tissue regeneration and has shown desirable results in vascular, bone repair, cartilage repair, and oral surgery.
- Also, the market players' key developments are expected to boost the growth of the segment. For instance, in October 2022, the hydrated human amnion membrane allograft by BioLab Sciences, Membrane Wrap - Hydro, was recognized by the United States Food and Drug Administration (US FDA) Tissue Reference Group (TRG) as a human cell, tissue/cellular/tissue-based product (HCT/P). The product is indicated for the management of surgical wounds and other wounds. Such recognition by the USFDA would enable the product to be easily reimbursed by the insurance bodies, which would make the product very affordable and in high demand.
- In September 2022, MiMedx Group Inc. launched its Amnioeffect, a tri-layer PURION-processed human tissue allograft consisting of the placenta's chorion, amnion, and intermediate membrane layers. The products offer suitable healing of the surgical wound. The company stated that the product launch would expand its surgical recovery product portfolio. Such developments would create more opportunities for the amniotic membrane to be used to manage surgical wounds, which would meet the high demand for surgical wound healing.
- Therefore, owing to the above factors, the surgical wounds segment is growing and is expected to grow significantly during the forecast period.
North America is Expected to Grow Significantly During the Forecast Period
- North America is the largest regional market in revenue, owing to high healthcare expenditure, highly developed healthcare infrastructure, and the recent developments by the market players. For instance, according to the data published by the United States Centers for Medicare & Medicaid Services in February 2023, the national healthcare expenditure increased by 2.7% to USD 4.3 trillion in 2021 compared to 2020.
- Also, the key developments by market players are anticipated to boost market growth in North America. For instance, in November 2022, Verséa announced rolling out the Biovance 3L ocular tri-layer human amniotic membrane.
- The rigorous research and development in countries across North America is expected to boost the amniotic membrane market growth in the region. For instance, in March 2023, at the annual meeting of the American Society of Cataract and Refractive Surgery (ASCRS) in Boston, ophthalmologists presented research shedding light on the application of cryopreserved amniotic membrane (CAM). A notable advancement included using BioTissue’s Prokera Slim to enhance the ocular surface in various clinical scenarios.
- Therefore, the market growth is expected in North America due to these factors.
Amniotic Membrane Industry Overview
The amniotic membrane market is moderately competitive due to the presence of a few companies operating globally and regionally. The competitive landscape includes an analysis of some international and local companies that hold market shares and are well known, including Human Regenerative Technologies LLC, Katena Products Inc., Mimdex, Amnio Technology LLC, TissueTech Inc. (BioTissue), Integra LifeSciences Corporation, Skye Biologics Inc., Amniox Medical Inc., Laboratoire CCD, Vivex Biologics Inc., Merakris Therapeutics, and Akorn Operating Company LLC.
Amniotic Membrane Market Leaders
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Human Regenerative Technologies, LLC
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Katena Products. Inc.
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MIMEDX
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Amnio Technology, LLC
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TissueTech, Inc. (BioTissue)
*Disclaimer: Major Players sorted in no particular order
Amniotic Membrane Market News
- April 2024: Xtant Medical Holdings Inc. officially rolled out two new amniotic membrane allografts: SimpliGraft and SimpliMax. These innovative products, available in single and dual-layer formats, are dehydrated and terminally irradiated. They are designed to act as protective barriers when applied topically to chronic and acute wounds, shielding them from the external environment.
- January 2023: Osaka-Gunze Limited announced that its subsidiary, Gunze Medical Limited, will commence sales of EPIFIX, a dehydrated human amnion/chorion membrane (dHACM) allograft, marking the first and only approved product of its kind in Japan.
Amniotic Membrane Market Report - Table of Contents
1. INTRODUCTION
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Rise in the Number of Accident and Trauma Cases
4.2.2 Increasing Awareness about the Benefits Offered by Amniotic Membrane
4.2.3 Rising Research on Stem Cell Biology and Regenerative Medicine
4.3 Market Restraints
4.3.1 Lack of Standardized Guidelines and Skilled Professionals
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION (Market Size by Value - USD)
5.1 By Enzyme
5.1.1 Cryopreserved Amniotic Membrane
5.1.2 Dehydrated Amniotic Membrane
5.2 By Application
5.2.1 Ophthalmology
5.2.2 Surgical Wounds
5.2.3 Other Applications
5.3 By End User
5.3.1 Hospitals
5.3.2 Ambulatory Surgical Centers
5.3.3 Other End Users
5.4 Geography
5.4.1 North America
5.4.1.1 United States
5.4.1.2 Canada
5.4.1.3 Mexico
5.4.2 Europe
5.4.2.1 Germany
5.4.2.2 United Kingdom
5.4.2.3 France
5.4.2.4 Italy
5.4.2.5 Spain
5.4.2.6 Rest of Europe
5.4.3 Asia-Pacific
5.4.3.1 China
5.4.3.2 Japan
5.4.3.3 India
5.4.3.4 Australia
5.4.3.5 South Korea
5.4.3.6 Rest of Asia-Pacific
5.4.4 Middle East and Africa
5.4.4.1 GCC
5.4.4.2 South Africa
5.4.4.3 Rest of Middle East and Africa
5.4.5 South America
5.4.5.1 Brazil
5.4.5.2 Argentina
5.4.5.3 Rest of South America
6. COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.1 Amnio Technology LLC
6.1.2 TissueTech Inc. (BioTissue)
6.1.3 Human Regenerative Technologies LLC
6.1.4 Katena Products Inc.
6.1.5 MIMEDX
6.1.6 Integra LifeSciences Corporation
6.1.7 Skye Biologics Inc.
6.1.8 Amniox Medical Inc.
6.1.9 Laboratoire CCD
6.1.10 VIVEX Biologics Inc.
6.1.11 Merakris Therapeutics
6.1.12 Thea Pharma
- *List Not Exhaustive
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
Amniotic Membrane Industry Segmentation
The amniotic membrane consists of a combination of tissues and cells, and it is the innermost layer of the placenta, which is widely used in ophthalmology and wound healing.
The amniotic membrane market is segmented by enzyme, application, end user, and geography. By enzymes, the market is segmented as cryopreserved amniotic membrane and dehydrated amniotic membrane. By application, the market is segmented as ophthalmology, surgical wounds, and other applications. By end user, the market is segmented as hospitals, ambulatory surgical centers, and other end users. By geography, the market is segmented as North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major regions globally.
The report offers the value (USD) for the above segments.
| By Enzyme | |
| Cryopreserved Amniotic Membrane | |
| Dehydrated Amniotic Membrane |
| By Application | |
| Ophthalmology | |
| Surgical Wounds | |
| Other Applications |
| By End User | |
| Hospitals | |
| Ambulatory Surgical Centers | |
| Other End Users |
| Geography | ||||||||
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Amniotic Membrane Market Research FAQs
How big is the Amniotic Membrane Market?
The Amniotic Membrane Market size is expected to reach USD 2.99 billion in 2024 and grow at a CAGR of 12.10% to reach USD 4.26 billion by 2029.
What is the current Amniotic Membrane Market size?
In 2024, the Amniotic Membrane Market size is expected to reach USD 2.99 billion.
Who are the key players in Amniotic Membrane Market?
Human Regenerative Technologies, LLC, Katena Products. Inc., MIMEDX, Amnio Technology, LLC and TissueTech, Inc. (BioTissue) are the major companies operating in the Amniotic Membrane Market.
Which is the fastest growing region in Amniotic Membrane Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in Amniotic Membrane Market?
In 2024, the North America accounts for the largest market share in Amniotic Membrane Market.
What years does this Amniotic Membrane Market cover, and what was the market size in 2023?
In 2023, the Amniotic Membrane Market size was estimated at USD 2.63 billion. The report covers the Amniotic Membrane Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Amniotic Membrane Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
Amniotic Membrane Industry Report
Statistics for the 2023 Amniotic Membrane market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Amniotic Membrane analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
