Market Trends of Alpha Emitter Industry
This section covers the major market trends shaping the Alpha Emitter Market according to our research experts:
Medical Application in Ovarian Cancer is Expected to Observe the Highest Growth Rate Over the Forecast Period
The ovarian cancer segment in the alpha emitter market is expected to witness the highest CAGR by the end of the forecast period.
The growth rate is attributed to an increasing number of new diagnosis cases. According to the American Cancer Society, ovarian cancer is the fifth most common cause of cancer-related death among women in the United States. It was estimated that about 21,410 women would receive a new diagnosis of ovarian cancer, while about 13,770 women would die from ovarian cancer in 2021. A recent Phase I clinical trial involving At-211-MX35 F (ab) showed significant efficacy, as therapeutic doses reached their targets in patients with ovarian cancer.
The major market players are focused on developing advanced radionuclides for the management of different types of ovarian cancer. For instance, in January 2021, Soricimed Biopharma Inc. and Orano Med agreed to focus on the development of a novel Peptide Receptor Radionuclide Therapy to treat solid tumor cancers. The companies use Orano Med's unique radioactive alpha emitter, lead-212 (212Pb), conjugated or linked to Soricimed's TRPV6 cancer receptor-targeting peptides to investigate the use of this novel approach in cancer treatment.
Ovarian cancer uses radioimmunotherapy as a locally injected adjuvant therapy. Trials have evaluated the practice of complete abdominal or moving-strip external-beam radiotherapy (EBRT) or non-specific IP radiotherapy, with colloid preparations of Au-198 or P-32 as adjuvant therapies. The adoption of targeted alpha therapy with higher LET and shorter wavelengths has been promising in the treatment process. This trend is expected to gain traction in the future.
North America Dominates the Market, and It is Expected to do the Same During the Forecast Period
Currently, North America dominates the alpha emitter market, and it is expected to continue its stronghold for a few more years due to the increase in cancer and cardiological diseases, which is the major driving factor for the market growth in the region. For instance, the diffusing alpha-emitter radiation therapy, Alpha DaRT, was found to elicit complete responses (CRs) per RECIST v1.1 criteria in 10 patients with malignant skin and soft tissue cancers in a trial. According to Sofer, Alpha Tau Medical Ltd is closer to launching a multi-center pivotal trial for skin cancer in the United States. This trial is being planned for launch in 2022.
In the United States, cancer is one of the most prevalent forms of cancer. As per the estimates of the American Cancer Society, in 2021, an estimated 1,898,160 new cases of cancer were diagnosed in the United States, and 608,570 people died from the disease. This number is likely to increase insignificantly in the future, which is driving the growth of the oncology segment in the United States, thereby propelling the alpha emitter market.
Moreover, according to the GLOBOCAN 2020 report, the number of new cancer cases was 274,364 in 2020, including prostate cancer 29,972, breast cancer 28,026, lung Cancer 25,574, colorectal cancer 25,510, bladder cancer 9,350, and other cancers 155,932. The rising prevalence of cancer is making it imperative for healthcare professionals across Canada to increase radiotherapy utilization for cancer treatment. This is directly affecting the growth of the alpha emitter market in the country.
