Market Trends of Global Advanced Drug Delivery Systems Industry
This section covers the major market trends shaping the Advanced Drug Delivery Systems Market according to our research experts:
The Oral Drug Delivery System Segment by Type to Hold the High Growth Over the Forecast Period
The oral drug delivery method is the most common and preferred drug administration route by the physician and the patient. The demand for this route of administration mostly lies in the convenience of intake and the availability of a broad window of the therapeutic index, which, in turn, lowers the possibility of toxicity and side effects.
With increasing costs and complications in developing, patenting, and marketing new drug entities, pharmaceutical companies, with simultaneous recognition of the therapeutic advantages of controlled drug delivery, are paying greater attention to developing and modifying oral-release drug delivery systems. Over the last decade, oral release drug delivery systems have received extensive attention owing to their flexibility, reduced dosing frequency, and better patient compliance. The aforesaid factors, in combination with the reasonable cost of oral controlled release drug delivery systems, led to greater adoption of this route of administration.
The accelerated pace of advanced oral drug delivery system development is fostered by a growing market of controlled release formulations and new launches in key therapeutic areas such as the central nervous system and cardiovascular, metabolic, and respiratory diseases. For instance, in 2020, Progenity Inc. reported positive preliminary preclinical data regarding the performance of its oral drug delivery system (DDS), the DDS capsule, which uses a proprietary autonomous localization technology designed to identify the ileal/ileocecal region of the GI tract. This technology is based on anatomy and is designed to resist variability in physiological conditions like pH, motility, and bacteria. The launch of such products will provide growth opportunities for the segment in the near future.
The demand for advanced drug delivery systems such as oral thin-film drugs is rising due to their high clinical efficacy and effectiveness against diseases. For instance, in June 2021, Shilpa Medicare Ltd. launched an oral thin film formulation, a pediatric dose of paracetamol oral thin film, under the brand name Molshil. Shilpa received approval for Molshil oral thin films after sufficiently complying with bioequivalence requirements. Shilpa's Paracetamol oral thin films are patent protected and are the first of their kind in the world.
Thus, owing to the abovementioned factors, the oral drug delivery segment is expected to grow during the forecast period.
North America Dominates the Market and is Expected to Follow the Same Trend Over the Forecast Period
North America currently dominates the global advanced drug delivery systems market owing to the better adoption of improved drug delivery solutions and follow-up of advanced treatment approaches in healthcare. The United States is the largest market in the region. The growing inclination toward self-administration of drugs, increasing innovations in injectable drug delivery systems, the high adoption rate of new healthcare technologies, and the high prevalence of chronic diseases are the primary drivers for the United States advanced drug delivery systems market.
Heart disease is a leading cause of death that burdens people, communities, healthcare providers, and systems in the country. Nearly half of all adults in the United States have some form of cardiovascular disease. According to the American Cancer Society, nearly 2 million new cancer cases are expected to be diagnosed, and around 609,000 people will die from cancer in the United States in 2022. Such a high burden of diseases creates demand for advanced drug delivery systems for effective treatment and thus drives the growth of the market.
Additionally, the joint initiatives taken by the market players, non-profit organizations, and government agencies are also propelling the growth of the market in the region. For instance, in March 2022, TFF Pharmaceuticals, Inc. entered into a Cooperative Research and Development Agreement (CRADA) with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), part of the United States Army Medical Research and Development Command and the United States Army's premier institution and facility for defensive research into countermeasures against biological warfare, and the Geneva Foundation, a non-profit that advances innovative medical research within the United States military. As per the agreement, TFF Pharmaceuticals and USAMRIID will evaluate the immune response of a dry powder recombinant Vesicular Stomatitis Virus Severe Acute Respiratory Syndrome Coronavirus-2 Glycoprotein (TFFD-rVSV-SARS2-GP) vaccine formulated using TFF's Thin Film Freezing technology. Such joint initiatives are also expected to propel the growth of the market.
Thus, owing to the abovementioned factors, the North American region is expected to show growth over the forecast period.
